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PHOSPHORYLATED CDK2-CYCLYIN A-SUBSTRATE PEPTIDE COMPLEX
1QMZ
Primary Citation
 
 
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  •   Molecular Description Hide
    Classification: Cell Cycle
    Structure Weight: 130529.90
    Molecule: CELL DIVISION PROTEIN KINASE 2
    Polymer: 1 Type: protein Length: 299
    Chains: A, C
    EC#: 2.7.11.22   
    Details: PHOSPHORYLATED
    Organism Homo sapiens
    Gene Names CDK2 CDKN2
    UniProtKB:   Protein Feature View | Search PDB | P24941  
    Molecule: G2/MITOTIC-SPECIFIC CYCLIN A
    Polymer: 2 Type: protein Length: 259
    Chains: B, D
    Fragment: RESIDUES 174-432
    Organism Homo sapiens
    Gene Names CCNA2 CCN1 CCNA
    UniProtKB:   Protein Feature View | Search PDB | P20248  
    Molecule: SUBSTRATE PEPTIDE
    Polymer: 3 Type: protein Length: 7
    Chains: E, F
    Fragment: 1-7
    Organism Homo sapiens
     
  •   Source Hide
    Polymer: 1
    Scientific Name: Homo sapiens   Taxonomy   Common Name: Human Expression System: Escherichia coli  
    Polymer: 2
    Scientific Name: Homo sapiens   Taxonomy   Common Name: Human Expression System: Escherichia coli  
    Polymer: 3
    Scientific Name: Synthetic construct (Homo sapiens)   Taxonomy    
     
  •   Related PDB Entries Hide
    Identifier Details
    1FIN  CYCLIN A - CYCLIN-DEPENDENT KINASE 2 COMPLEX 
    1JST  PHOSPHORYLATED CYCLIN-DEPENDENT KINASE-2 BOUND TO CYCLIN A 
    1JSU  P27(KIP1)/CYCLIN A/CDK2 COMPLEX 
     
  •   Ligand Chemical Component Hide
    Identifier Formula Name Interactions
    ATP
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    Download      		ATP C10 H16 N5 O13 P3
    ADENOSINE-5'-TRIPHOSPHATE
    		ATP:1QMZ
    MG
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    Download      		MG Mg
    MAGNESIUM ION
     
  •   Modified Residues Hide
    Identifier Formula Parent Type
    TPO
    Search      		TPO C4 H10 N O6 P THR lPeptideLinking
     
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Data in orange boxes are gathered from external resources (when available).
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  Biological Assembly       
Biological assembly 1 generated by PQS (software)
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  •   Deposition Summary Hide
    Authors:   Brown, N.R.,  Noble, M.E.M.,  Endicott, J.A.,  Johnson, L.N.

    Deposition:   1999-10-11
    Release:   1999-12-14
    Last Modified (REVDAT):   2009-02-24
     
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    2011-07-13
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  •   Experimental Details Hide
    Method:   X-RAY DIFFRACTION
    Exp. Data:
    N/A
    Resolution[Å]:   2.20
    R-Value: 0.220 (work)
    R-Free: 0.280
    Space Group: P 21 21 2
    Unit Cell:
      Length [Å] Angles [°]
    a = 152.60 α = 90.00 
    b = 163.70 β = 90.00 
    c = 73.30 γ = 90.00