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Crystal Structure of E. coli purine nucleoside phosphorylase complexed with 9-beta-D-arabinofuranosyladenine and sulfate/phosphate
1PW7
Primary Citation
 
 
  •   Molecular Description Hide
    Classification: Transferase
    Structure Weight: 79032.94
    Molecule: Purine nucleoside phosphorylase
    Polymer: 1 Type: protein Length: 239
    Chains: A, B, C
    EC#: 2.4.2.1   
    Organism: Escherichia coli Escherichia coli O157:H7
    Gene Names: deoD Z5986 ECs5343
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  •   Source Hide
    Polymer: 1
    Scientific Name: Escherichia coli, escherichia coli o157:h7   Taxonomy   Common Name: ,  
     
  •   Related PDB Entries Hide
    Identifier Details
    1ECP  E. coli PNP 
    1K9S  E. coli PNP with formycin A analog 
    1PK7  E. coli PNP with adenosine 
    1PKE  E. coli PNP with 2-fluoro-2'-deoxyadenosine 
    1PR0  Escherichia coli Purine Nucleoside Phosphorylase Complexed with Inosine and Phosphate/Sulfate 
    1PR1  Escherichia coli Purine Nucleoside Phosphorylase Complexed with Formycin B and Phosphate/Sulfate 
    1PR2  Escherichia coli Purine Nucleoside Phosphorylase Complexed with 9-beta-D-[2-deoxyribofuranosyl]-6-methylpurine and Phosphate/Sulfate 
    1PR4  Escherichia coli Purine Nucleoside Phosphorylase Complexed with 9-beta-D-ribofuranosyl-6-methylthiopurine and Phosphate/Sulfate 
    1PR5  Escherichia coli Purine Nucleoside Phosphorylase Complexed with 7-deazaadenosine and Phosphate/Sulfate 
    1PR6  Escherichia coli Purine Nucleoside Phosphorylase Complexed with 9-beta-D-xylofuranosyladenine and Phosphate/Sulfate 
     
  •   Ligand Chemical Component Hide
    Identifier Formula Name View Interactions
    PO4
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    PO4 O4 P
    PHOSPHATE ION
    RAB
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    RAB C10 H13 N5 O4
    2-(6-AMINO-PURIN-9-YL)-5-HYDROXYMETHYL-TETRAHYDRO- FURAN-3,4-DIOL
    RAB:1PW7
     
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Data in orange boxes are gathered from external resources (when available).
 
  Biological Assembly       
Biological assembly 1 assigned by authors and generated by PISA,PQS (software)
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  •   Deposition Summary Hide
    Authors:   Bennett, E.M.,  Li, C.,  Allan, P.W.,  Parker, W.B.,  Ealick, S.E.

    Deposition:   2003-06-30
    Release:   2003-11-25
    Last Modified (REVDAT):   2011-11-16
     
  •   Revision History    Hide
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    2011-11-16
    Atom occupancy
    2011-07-13
    Biological assembly
    2011-07-13
    Version format compliance
     
  •   Experimental Details Hide
    Method:   X-RAY DIFFRACTION
    Exp. Data:
      Structure Factors
    EDS  
    Resolution[Å]:   2.00
    R-Value: 0.221 (obs.)
    R-Free: 0.246
    Space Group: P 61 2 2
    Unit Cell:
      Length [Å] Angles [°]
    a = 121.50 α = 90.00 
    b = 121.50 β = 90.00 
    c = 242.20 γ = 120.00