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Structure of the Escherichia coli ClC Chloride channel and Fab Complex
 
 
DOI:10.2210/pdb1ots/pdb
1OTS
 
Primary Citation
spinning wheel
 
 
  •  
    Move Section Molecular Description Hide
    Classification: Membrane Protein
    Structure Weight: 193283.81
     
    Molecule:Voltage-gated ClC-type chloride channel eriC
    Polymer:1Type:polypeptide(L)Length:465
    Chains:A, B
    Molecule:Fab fragment (heavy chain)
    Polymer:2Type:polypeptide(L)Length:222
    Chains:C, E
    Molecule:Fab fragment (light chain)
    Polymer:3Type:polypeptide(L)Length:211
    Chains:D, F
     
     
  •  
    Move Section Source Hide
    Polymer: 1
    Scientific Name: Escherichia coli Go to NCBI Taxonomy entry Expression System: Escherichia coli bl21(de3)  
    Polymer: 2
    Scientific Name: Mus musculus Go to NCBI Taxonomy entry Common Name: House mouse  
    Polymer: 3
    Scientific Name: Mus musculus Go to NCBI Taxonomy entry Common Name: House mouse  
     
     
  •  
    Move Section Related PDB Entries Hide
    Id Details
    1OTT  EcClC Fab Complex E148A mutant 
    1OTU  EcClC Fab Complex E148Q mutant 
     
     
  •  
    Move Section Ligand Chemical Component Hide
    Identifier Name Formula Interaction View Links
    CL     CHLORIDE ION Cl 3DLigand Explorer Link out to Ligand Expos:CL Link out to SuperLigands:CL Link out to SuperHapten:CL
     
     
  •  
    Move Section Derived Data Hide
     
     
 
 
  •  
    Move Section Deposition Summary Hide
    Authors:   Dutzler, R.,   Campbell, E.B.,   MacKinnon, R.

    Deposition:   2003-03-22
    Release:   2003-04-15
    Last Modified (REVDAT):   2009-02-24
     
     
  •  
    Move Section Experimental Details Hide
    Method:   X-RAY DIFFRACTION
    Experimental Data:   Download Structure Factors  [ EDS External Link to EDS ]
    View a histogram of Resolution Resolution[Å]: 2.51
    R-Value: 0.264 (obs.)
    R-Free: 0.299
    Space Group: C 2
    Unit Cell:
      Length [Å] Angles [°]
    a = 229.94 α = 90.00 
    b = 93.87 β = 131.72 
    c = 168.54 γ = 90.00