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X-ray structure of a voltage-dependent potassium channel in complex with an Fab
 
 
DOI:10.2210/pdb1orq/pdb
1ORQ
 
Primary Citation
spinning wheel
 
 
  •  
    Move Section Molecular Description Hide
    Classification: Membrane Protein
    Structure Weight: 72603.26
     
    Molecule:6E1 Fab light chain
    Polymer:1Type:polypeptide(L)Length:215
    Chains:A
    Molecule:6E1 Fab heavy chain
    Polymer:2Type:polypeptide(L)Length:219
    Chains:B
    Molecule:potassium channel
    Polymer:3Type:polypeptide(L)Length:223
    Chains:C
    Fragment:KvAP
    Mutation:Y46C
     
     
  •  
    Move Section Source Hide
    Polymer: 1
    Scientific Name: Mus musculus Go to NCBI Taxonomy entry Common Name: House mouse  
    Polymer: 2
    Scientific Name: Mus musculus Go to NCBI Taxonomy entry Common Name: House mouse  
    Polymer: 3
    Scientific Name: Aeropyrum pernix Go to NCBI Taxonomy entry Expression System: Escherichia coli  
     
     
  •  
    Move Section Related PDB Entries Hide
    Id Details
    1ORS  X-ray structure of the KvAP potassium channel voltage sensor in complex with an Fab 
     
     
  •  
    Move Section Ligand Chemical Component Hide
    Identifier Name Formula Interaction View Links
    CD     CADMIUM ION Cd 3DLigand Explorer Link out to Ligand Expos:CD Link out to SuperLigands:CD Link out to SuperHapten:CD
    K     POTASSIUM ION K 3DLigand Explorer Link out to Ligand Expos:K Link out to SuperLigands:K Link out to SuperHapten:K
     
     
  •  
    Move Section Derived Data Hide
     
     
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  •  
    Move Section Deposition Summary Hide
    Authors:   Jiang, Y.,   Lee, A.,   Chen, J.,   Ruta, V.,   Cadene, M.,   Chait, B.T.,   MacKinnon, R.

    Deposition:   2003-03-14
    Release:   2003-05-06
    Last Modified (REVDAT):   2009-02-24
     
     
  •  
    Move Section Experimental Details Hide
    Method:   X-RAY DIFFRACTION
    Experimental Data:   Download Structure Factors  [ EDS External Link to EDS ]
    View a histogram of Resolution Resolution[Å]: 3.20
    R-Value: 0.253 (obs.)
    R-Free: 0.298
    Space Group: I 4 2 2
    Unit Cell:
      Length [Å] Angles [°]
    a = 189.44 α = 90.00 
    b = 189.44 β = 90.00 
    c = 150.48 γ = 90.00