Nitroreductase from e-coli in complex with the dinitrobenzamide prodrug SN23862 DOI:10.2210/pdb1oo6/pdb

1OO6   Display Files  close FASTA Sequence PDB File PDB File (Header) mmCIF File mmCIF File (Header) PDBML/XML File PDBML/XML File (Header)   Download Files  close FASTA Sequence PDB File (Text) PDB File (gz) mmCIF File mmCIF File (gz) PDBML/XML File PDBML/XML File (gz) Structure Factor (Text) Structure Factor (gz) Biological Assembly (gz) (A+S)   Share this Page  close Facebook Twitter LinkedIn Email Link this Page

Primary Citation       Related Citations in PDB Entry (REMARK 1) Hide     Molecular Description Hide Classification: Oxidoreductase Structure Weight: 49489.79 Molecule: Oxygen-insensitive NAD(P)H nitroreductase Polymer: 1 Type: protein Length: 217 Chains: A, B EC#: 1.5.1.34    Organism Escherichia coli Gene Names nfnB dprA nfsB nfsI ntr b0578 JW0567 UniProtKB:   Protein Feature View | Search PDB | P38489         Source Hide Polymer: 1 Scientific Name: Escherichia coli   Taxonomy   Expression System: Escherichia coli k12       Related PDB Entries Hide Identifier Details 1IDT  The same protein complexed with CB1954  1OO5  The same protein uncomplexed but with reduced FMN  1OON  The same protein complexed with SN27217  1OOQ  The same protein complexed with dicoumarol      Ligand Chemical Component Hide Identifier Formula Name Interactions FMN Search  Download  C17 H21 N4 O9 P FLAVIN MONONUCLEOTIDE   Ligand Explorer SN2 Search  Download  C11 H12 Cl2 N4 O5 5-[BIS-2(CHLORO-ETHYL)-AMINO]-2,4-DINTRO- BENZAMIDE   Ligand Explorer     External Domain Annotations Hide SCOP Classification v1.75: 2 Domains - data from SCOP   CATH Classification v3.4.0: 2 Domains - data from CATH   Pfam Classification: 1 Domain - data from Pfam   GO Terms: 8 Terms - data from GO      Structural Biology Knowledgebase Data Hide     Data in orange boxes are gathered from external resources (when available). Reset Layout

Biological Assembly            View in 3D More Images... Biological assembly 1 assigned by authors and generated by PISA (software) Downloadable viewers: Simple Viewer Protein Workshop Ligand Explorer Kiosk Viewer Other Viewers  KiNG WebMol QuickPDB FirstGlance         MyPDB Personal Annotations Hide     Deposition Summary Hide Authors:   Johansson, E.,  Parkinson, G.N.,  Denny, W.A.,  Neidle, S. Deposition:   2003-03-03 Release:   2003-04-08 Last Modified (REVDAT):   2009-02-24     Revision History    Hide Mouse over text for details 2011-07-13 Version format compliance     Experimental Details Hide Method:   X-RAY DIFFRACTION Exp. Data:   Structure Factors EDS   Resolution[Å]:   2.00 R-Value: 0.231 (obs.) R-Free: 0.286 Space Group: P 41 21 2 Unit Cell:   Length [Å] Angles [°] a = 57.69 α = 90.00  b = 57.69 β = 90.00  c = 266.67 γ = 90.00