Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-Directed Serine Protease Inhibitors DOI:10.2210/pdb1o3l/pdb

1O3L   Display Files  close FASTA Sequence PDB File PDB File (Header) mmCIF File mmCIF File (Header) PDBML/XML File PDBML/XML File (Header)   Download Files  close FASTA Sequence PDB File (Text) PDB File (gz) mmCIF File mmCIF File (gz) PDBML/XML File PDBML/XML File (gz) Structure Factor (Text) Structure Factor (gz) Biological Assembly (gz) (A)   Share this Page  close Facebook Twitter LinkedIn Email Link this Page

Primary Citation       Related Citations in PDB Entry (REMARK 1) Hide     Molecular Description Hide Classification: Hydrolase Structure Weight: 23787.15 Molecule: BETA-TRYPSIN Polymer: 1 Type: protein Length: 223 Chains: A EC#: 3.4.21.4    Organism Bos taurus UniProtKB:   Protein Feature View | Search PDB | P00760         Source Hide Polymer: 1 Scientific Name: Bos taurus   Taxonomy   Common Name: Cattle       Related PDB Entries Hide Identifier Details 1C5R  Bovine trypsin complex with different inhibitor      Ligand Chemical Component Hide Identifier Formula Name Interactions 678 Search  Download  C17 H13 Br N3 O3 (3-{5-[AMINO(IMINIO)METHYL]-1H-INDOL-2-YL}- 5-BROMO-4-OXIDOPHENYL)ACETATE   Ligand Explorer CA Search  Download  Ca CALCIUM ION   Ligand Explorer CL Search  Download  Cl CHLORIDE ION   Ligand Explorer     External Ligand Annotations Hide Identifier   Binding Affinity (Sequence Identity %) 678 Search  Download  N/A in BindingDB N/A in BindingMoad Ki: 290 nM - data from PDBbind       External Domain Annotations Hide SCOP Classification v1.75: 1 Domain - data from SCOP   CATH Classification v3.4.0: 2 Domains - data from CATH   Pfam Classification: 1 Domain - data from Pfam   GO Terms: 9 Terms - data from GO      Structural Biology Knowledgebase Data Hide     Data in orange boxes are gathered from external resources (when available). Reset Layout

Biological Assembly            View in 3D More Images... Biological assembly 1 assigned by authors Downloadable viewers: Simple Viewer Protein Workshop Ligand Explorer Kiosk Viewer Other Viewers  KiNG WebMol QuickPDB FirstGlance         MyPDB Personal Annotations Hide     Deposition Summary Hide Authors:   Katz, B.A.,  Elrod, K.,  Verner, E.,  Mackman, R.L.,  Luong, C.,  Shrader, W.D.,  Sendzik, M.,  Spencer, J.R.,  Sprengeler, P.A.,  Kolesnikov, A.,  Tai, V.W.,  Hui, H.C.,  Breitenbucher, J.G.,  Allen, D.,  Janc, J.W. Deposition:   2003-03-06 Release:   2003-09-02 Last Modified (REVDAT):   2009-02-24     Revision History    Hide Mouse over text for details 2011-07-13 Version format compliance     Experimental Details Hide Method:   X-RAY DIFFRACTION Exp. Data:   Structure Factors EDS   Resolution[Å]:   1.40 R-Value: 0.208 (obs.) R-Free: 0.220 Space Group: P 21 21 21 Unit Cell:   Length [Å] Angles [°] a = 63.73 α = 90.00  b = 63.33 β = 90.00  c = 69.26 γ = 90.00      Molecule of the Month Hide Thrombin Trypsin Serpins Tissue Factor Fibrin