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CRYSTAL STRUCTURE OF HUMAN CHITOTRIOSIDASE IN COMPLEX WITH CHITOBIOSE
1LG1
Primary Citation
 
 
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  •   Molecular Description Hide
    Classification: Hydrolase
    Structure Weight: 41209.51
    Molecule: chitotriosidase
    Polymer: 1 Type: protein Length: 365
    Chains: A
    EC#: 3.2.1.14   
    Fragment: residues 22-386
    Organism Homo sapiens
    Gene Name CHIT1
    UniProtKB:   Protein Feature View | Search PDB | Q13231  
     
  •   Source Hide
    Polymer: 1
    Scientific Name: Homo sapiens   Taxonomy   Common Name: Human Expression System: Mesocricetus auratus  
    Polymer: 2
    Scientific Name: Synthetic construct   Taxonomy    
     
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    Identifier Details
    1GUV  Structure of human chitotriosidase 
    1lg2  Structure of human chitotriosidase in complex with ethylene glycol 
     
  •   Ligand Chemical Component Hide
    Identifier Formula Name Interactions
    NAG
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    NAG C8 H15 N O6
    N-ACETYL-D-GLUCOSAMINE
    NAG:1LG1
     
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Data in orange boxes are gathered from external resources (when available).
 
 
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  •   Deposition Summary Hide
    Authors:   Fusetti, F.,  Rozeboom, H.J.,  Dijkstra, B.W.

    Deposition:   2002-04-14
    Release:   2002-09-18
    Last Modified (REVDAT):   2011-07-13
     
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    2011-07-13
    Non-polymer description
    2011-07-13
    Version format compliance
     
  •   Experimental Details Hide
    Method:   X-RAY DIFFRACTION
    Exp. Data:
      Structure Factors
    EDS  
    Resolution[Å]:   2.78
    R-Value: 0.204 (obs.)
    R-Free: 0.269
    Space Group: P 43 21 2
    Unit Cell:
      Length [Å] Angles [°]
    a = 94.40 α = 90.00 
    b = 94.40 β = 90.00 
    c = 87.98 γ = 90.00