1H1K

THE BLUETONGUE VIRUS (BTV) CORE BINDS DSRNA


Experimental Data Snapshot

  • Method: X-RAY DIFFRACTION
  • Resolution: 10.0 Å

wwPDB Validation   3D Report Full Report


This is version 1.2 of the entry. See complete history


Literature

The Core of Bluetongue Virus Binds Double-Stranded RNA

Diprose, J.M.Grimes, J.M.Sutton, G.C.Burroughs, J.N.Meyer, A.Maan, S.Mertens, P.P.C.Stuart, D.I.

(2002) J Virol 76: 9533

  • DOI: https://doi.org/10.1128/jvi.76.18.9533-9536.2002
  • Primary Citation of Related Structures:  
    1H1K

  • PubMed Abstract: 

    Double-stranded RNA (dsRNA) viruses conceal their genome from the host to avoid triggering unfavorable cellular responses. The crystal structure of the core of one such virus, bluetongue virus, reveals an outer surface festooned with dsRNA. This may represent a deliberate strategy to sequester dsRNA released from damaged particles to prevent host cell shutoff.


  • Organizational Affiliation

    Division of Structural Biology, Wellcome Trust Centre for Human Genetics, Headington, Oxford OX3 7BN, United Kingdom.


Macromolecules
Find similar nucleic acids by:  (by identity cutoff)  |  3D Structure
Entity ID: 1
MoleculeChains LengthOrganismImage
RNAA [auth I]412Bluetongue virus
Sequence Annotations
Expand
  • Reference Sequence
Find similar nucleic acids by:  (by identity cutoff)  |  3D Structure
Entity ID: 2
MoleculeChains LengthOrganismImage
RNAB [auth J]276Bluetongue virus
Sequence Annotations
Expand
  • Reference Sequence
Find similar nucleic acids by:  (by identity cutoff)  |  3D Structure
Entity ID: 3
MoleculeChains LengthOrganismImage
RNAC [auth K]265Bluetongue virus
Sequence Annotations
Expand
  • Reference Sequence
Find similar nucleic acids by:  (by identity cutoff)  |  3D Structure
Entity ID: 4
MoleculeChains LengthOrganismImage
RNAD [auth L]412Bluetongue virus
Sequence Annotations
Expand
  • Reference Sequence
Find similar nucleic acids by:  (by identity cutoff)  |  3D Structure
Entity ID: 5
MoleculeChains LengthOrganismImage
RNAE [auth M]276Bluetongue virus
Sequence Annotations
Expand
  • Reference Sequence
Find similar nucleic acids by:  (by identity cutoff)  |  3D Structure
Entity ID: 6
MoleculeChains LengthOrganismImage
RNAF [auth N]265Bluetongue virus
Sequence Annotations
Expand
  • Reference Sequence
Experimental Data & Validation

Experimental Data

  • Method: X-RAY DIFFRACTION
  • Resolution: 10.0 Å
  • Space Group: P 21 21 2
Unit Cell:
Length ( Å )Angle ( ˚ )
a = 795.6α = 90
b = 821.8β = 90
c = 753.3γ = 90
Software Package:
Software NamePurpose
CNSrefinement
DENZOdata reduction
SCALEPACKdata scaling
CNSphasing

Structure Validation

View Full Validation Report



Entry History 

Deposition Data

Revision History  (Full details and data files)

  • Version 1.0: 2002-09-26
    Type: Initial release
  • Version 1.1: 2011-05-08
    Changes: Version format compliance
  • Version 1.2: 2011-07-13
    Changes: Version format compliance