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CRYSTAL STRUCTURE OF LACTOCOCCUS LACTIS DIHYDROOROTATE DEHYDROGENASE B COMPLEXED WITH OROTATE
1EP2
Primary Citation
 
 
  •   Molecular Description Hide
    Classification: Oxidoreductase
    Structure Weight: 63110.62
    Molecule: DIHYDROOROTATE DEHYDROGENASE B (PYRD SUBUNIT)
    Polymer: 1 Type: protein Length: 311
    Chains: A
    EC#: 1.3.1.14   
    Organism: Lactococcus lactis
    Gene Names: pyrDB llmg_1106
    UniProtKB: Protein Feature View | Search PDB | P54322  
    Molecule: DIHYDROOROTATE DEHYDROGENASE B (PYRK SUBUNIT)
    Polymer: 2 Type: protein Length: 261
    Chains: B
    EC#: 1.3.98.1   
    Organism: Lactococcus lactis
    Gene Names: pyrK llmg_1105
    UniProtKB: Protein Feature View | Search PDB | P56968  
     
  •   Structure Validation Hide

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  •   Related Citations in PDB Entry (REMARK 1) Hide
     
  •   Source Hide
    Polymer: 1
    Scientific Name: Lactococcus lactis   Taxonomy   Expression System: Escherichia coli  
    Polymer: 2
    Scientific Name: Lactococcus lactis   Taxonomy   Expression System: Escherichia coli  
     
  •   Related PDB Entries Hide
    Identifier Details
    1EP1  Crystal structure of Lactococcus lactis Dihydroorotate dehydrogenase B at room temperature. 
    1EP3  Crystal structure of Lactococcus lactis Dihydroorotate dehydrogenase B. Data collected under cryogenic conditions. 
     
  •   Ligand Chemical Component Hide
    Identifier Formula Name View Interactions
    FAD
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    FAD C27 H33 N9 O15 P2
    FLAVIN-ADENINE DINUCLEOTIDE
    FAD:1EP2
    FES
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    FES Fe2 S2
    FE2/S2 (INORGANIC) CLUSTER
    FMN
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    FMN C17 H21 N4 O9 P
    FLAVIN MONONUCLEOTIDE
    FMN:1EP2
    ORO
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    ORO C5 H4 N2 O4
    OROTIC ACID
    ORO:1EP2
     
  •   External Domain Annotations Hide
     
  •   Structural Biology Knowledgebase Data Hide
     
 
Data in orange boxes are gathered from external resources (when available).
 
  Biological Assembly       
Biological assembly 1 assigned by authors and generated by PISA,PQS (software)
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  •   Deposition Summary Hide
    Authors:   Rowland, P.,  Norager, S.,  Jensen, K.F.,  Larsen, S.

    Deposition:   2000-03-27
    Release:   2001-01-17
    Last Modified (REVDAT):   2011-07-13
     
  •   Revision History    Hide
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    2011-07-13
    Version format compliance
    2011-07-13
    Biological assembly
     
  •   Experimental Details Hide
    Method:   X-RAY DIFFRACTION
    Exp. Data:
    N/A
    Resolution[Å]:   2.40
    R-Value: 0.190 (work)
    R-Free: 0.241
    Space Group: H 3 2
    Unit Cell:
      Length [Å] Angles [°]
    a = 202.42 α = 90.00 
    b = 202.42 β = 90.00 
    c = 80.88 γ = 120.00