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CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR: SOLUTION STRUCTURES OF PEPTIDES BASED ON THE PHE508 REGION, THE MOST COMMON SITE OF DISEASE-CAUSING DELTA-F508 MUTATION
1CKW
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  •   Molecular Description Hide
    Classification: Metal Transport
    Structure Weight: 2907.37
    Molecule: PROTEIN (CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR (CFTR))
    Polymer: 1 Type: protein Length: 25
    Chains: A
    EC#: 3.6.3.49   
    Fragment: F508 MUTATION REGION
    Details: P25 PEPTIDE IN TRIFLUROETHANOL
    Gene Names CFTR ABCC7
    UniProtKB:   Protein Feature View | Search PDB | Q00555  
     
  •   Source Hide
    Polymer: 1
    Scientific Name: Synthetic construct   Taxonomy    
     
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  •   Deposition Summary Hide
    Authors:   Massiah, M.A.,  Ko, Y.H.,  Pedersen, P.L.,  Mildvan, A.S.

    Deposition:   1999-04-26
    Release:   1999-05-04
    Last Modified (REVDAT):   2009-02-24
     
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    2011-07-13
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  •   Experimental Details Hide
    Method:   SOLUTION NMR
    Exp. Data:
      NMR Restraints
    NMR Restraint Grid  
    BMRB  
    NMR Ensemble
    Conformers Calculated:     13
    Conformers Submitted:     13
    Selection Criteria: LEAST RESTRAINTS VIOLATIONS AND LOW ENERGY
    NMR Refine
    Method: SOLUTION NMR