SIS

(1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2S,3R)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl]oxy}-2-hydroxycyclohexyl 3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranoside


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Chemical Component Summary

Name(1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2S,3R)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl]oxy}-2-hydroxycyclohexyl 3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranoside
SynonymsSisomicin
Identifiers(2R,3R,4R,5R)-2-[(1S,2S,3R,4S,6R)-3-[[(2S,3R)-6-(aminomethyl)-3-azanyl-3,4-dihydro-2H-pyran-2-yl]oxy]-4,6-bis(azanyl)-2-oxidanyl-cyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol
FormulaC19 H37 N5 O7
Molecular Weight447.526
TypeNON-POLYMER
Isomeric SMILESC[C@@]1(CO[C@@H]([C@@H]([C@H]1NC)O)O[C@H]2[C@@H](C[C@@H]([C@H]([C@@H]2O)O[C@@H]3[C@@H](CC=C(O3)CN)N)N)N)O
InChIInChI=1S/C19H37N5O7/c1-19(27)7-28-18(13(26)16(19)24-2)31-15-11(23)5-10(22)14(12(15)25)30-17-9(21)4-3-8(6-20)29-17/h3,9-18,24-27H,4-7,20-23H2,1-2H3/t9-,10+,11-,12+,13-,14-,15+,16-,17-,18-,19+/m1/s1
InChIKeyURWAJWIAIPFPJE-YFMIWBNJSA-N

Chemical Details

Formal Charge0
Atom Count68
Chiral Atom Count11
Bond Count70
Aromatic Bond Count0

Drug Info: DrugBank

DrugBank IDDB12604 
NameSisomicin
Groups investigational
DescriptionSisomicin has been used in trials studying the treatment of Pyoderma.
SynonymsSisomicin
Categories
  • Agents that produce neuromuscular block (indirect)
  • Aminoglycoside Antibacterials
  • Anti-Bacterial Agents
  • Anti-Infective Agents
  • Antibacterials for Systemic Use
ATC-CodeJ01GB08
CAS number32385-11-8

Related Resource References

Resource NameReference
PubChem 36119
ChEMBL CHEMBL221886
ChEBI CHEBI:9169