SGP
GUANOSINE-2',3'-CYCLOPHOSPHOROTHIOATE
Find entries where: SGP
is present as a standalone ligand in 7 entries
as a non-polymer is covalently linked to polymer or other heterogen groups 1 entries
Chemical Component Summary | |
|---|---|
| Name | GUANOSINE-2',3'-CYCLOPHOSPHOROTHIOATE |
| Identifiers | 2-amino-9-[(1R,3S,5R,6R,8R)-3-hydroxy-8-(hydroxymethyl)-3-sulfanylidene-2,4,7-trioxa-3$l^{5}-phosphabicyclo[3.3.0]octan-6-yl]-1H-purin-6-one |
| Formula | C10 H12 N5 O6 P S |
| Molecular Weight | 361.271 |
| Type | NON-POLYMER |
| Isomeric SMILES | c1nc2c(n1[C@H]3[C@H]4[C@@H]([C@H](O3)CO)O[P@](=S)(O4)O)N=C(NC2=O)N |
| InChI | InChI=1S/C10H12N5O6PS/c11-10-13-7-4(8(17)14-10)12-2-15(7)9-6-5(3(1-16)19-9)20-22(18,23)21-6/h2-3,5-6,9,16H,1H2,(H,18,23)(H3,11,13,14,17)/t3-,5-,6-,9-,22+/m1/s1 |
| InChIKey | QZEROIIFJLCOOE-FHIGPPGSSA-N |
Chemical Details | |
|---|---|
| Formal Charge | 0 |
| Atom Count | 35 |
| Chiral Atom Count | 5 |
| Bond Count | 38 |
| Aromatic Bond Count | 5 |
Drug Info: DrugBank
| DrugBank ID | DB03178 |
|---|---|
| Name | Guanosine-2',3'-cyclophosphorothioate |
| Groups | experimental |
| Synonyms | Guanosine-2',3'-cyclophosphorothioate |
| CAS number | 38557-85-6 |
Drug Targets
| Name | Target Sequence | Pharmacological Action | Actions |
|---|---|---|---|
| Guanyl-specific ribonuclease Sa | DVSGTVCLSALPPEATDTLNLIASDGPFPYSQDGVVFQNRESVLPTQSYG... | unknown |
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison
T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS.
Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682
