SEC

SELENOCYSTEINE

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is present as a standalone ligand in 3 entries

as a non-polymer is covalently linked to polymer or other heterogen groups 6 entries

is present in a polymer sequence 85 entries

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Chemical Component Summary
Name	SELENOCYSTEINE
Identifiers	(2R)-2-azanyl-3-selanyl-propanoic acid
Formula	C₃ H₇ N O₂ Se
Molecular Weight	168.053
Type	L-PEPTIDE LINKING
Isomeric SMILES	C([C@@H](C(=O)O)N)[SeH]
InChI	InChI=1S/C3H7NO2Se/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/t2-/m0/s1
InChIKey	ZKZBPNGNEQAJSX-REOHCLBHSA-N

Chemical Details
Formal Charge	0
Atom Count	14
Chiral Atom Count	1
Bond Count	13
Aromatic Bond Count	0

Drug Info: DrugBank

DrugBank ID	DB02345
Name	Selenocysteine
Groups	experimental
Description	A naturally occurring amino acid in both eukaryotic and prokaryotic organisms. It is found in tRNAs and in the catalytic site of some enzymes. The genes for glutathione peroxidase and formate dehydrogenase contain the TGA codon, which codes for this amino acid. [PubChem]
Synonyms	L-selenocysteine Selenium cysteine Selenocysteine 3-selenyl-L-alanine
Brand Names	Dialyvite 5000 Dialyvite Supreme D Dialyvite 3000
Categories	Amino Acids Amino Acids, Peptides, and Proteins Amino Acids, Sulfur Cysteine Organoselenium Compounds Proteinogenic Amino Acids Selenium Compounds Sulfur Compounds
CAS number	10236-58-5

Drug Targets

Name	Target Sequence	Pharmacological Action
Cathelicidin antimicrobial peptide	MKTQRDGHSLGRWSLVLLLLGLVMPLAIIAQVLSYKEAVLRAIDGINQRS...	unknown
Nucleoside diphosphate kinase A	MANCERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVGLKFMQASEDLLKE...	unknown
Formate dehydrogenase H	MKKVVTVCPYCASGCKINLVVDNGKIVRAEAAQGKTNQGTLCLKGYYGWD...	unknown
Cysteine desulfurase	MIFSVDKVRADFPVLSREVNGLPLAYLDSAASAQKPSQVIDAEAEFYRHG...	unknown

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682