RX5

methyl (2-{(R)-(3-chlorophenyl)[(3R)-1-({(2S)-2-(methylamino)-3-[(3R)-tetrahydro-2H-pyran-3-yl]propyl}carbamoyl)piperidin-3-yl] methoxy}ethyl)carbamate


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Chemical Component Summary

Namemethyl (2-{(R)-(3-chlorophenyl)[(3R)-1-({(2S)-2-(methylamino)-3-[(3R)-tetrahydro-2H-pyran-3-yl]propyl}carbamoyl)piperidin-3-yl] methoxy}ethyl)carbamate
SynonymsVTP-27999
Identifiersmethyl N-[2-[(R)-(3-chlorophenyl)-[(3R)-1-[[(2S)-2-(methylamino)-3-[(3R)-oxan-3-yl]propyl]carbamoyl]piperidin-3-yl]methoxy]ethyl]carbamate
FormulaC26 H41 Cl N4 O5
Molecular Weight525.081
TypeNON-POLYMER
Isomeric SMILESCN[C@@H](C[C@H]1CCCOC1)CNC(=O)N2CCC[C@H](C2)[C@H](c3cccc(c3)Cl)OCCNC(=O)OC
InChIInChI=1S/C26H41ClN4O5/c1-28-23(14-19-6-5-12-35-18-19)16-30-25(32)31-11-4-8-21(17-31)24(20-7-3-9-22(27)15-20)36-13-10-29-26(33)34-2/h3,7,9,15,19,21,23-24,28H,4-6,8,10-14,16-18H2,1-2H3,(H,29,33)(H,30,32)/t19-,21-,23+,24+/m1/s1
InChIKeyNXWASIVXQMMPLM-ZXMXYHOLSA-N

Chemical Details

Formal Charge0
Atom Count77
Chiral Atom Count4
Bond Count79
Aromatic Bond Count6

Drug Info: DrugBank

DrugBank IDDB12416 
NameVTP-27999
Groups investigational
DescriptionVTP-27999 has been used in trials studying the basic science of Renal Function.
SynonymsVTP-27999
Categories
  • Acids, Acyclic
  • Agents Acting on the Renin-Angiotensin System
  • Renin Inhibitors
CAS number942142-51-0

Related Resource References

Resource NameReference
Pharos CHEMBL1276678
PubChem 16126898
ChEMBL CHEMBL1276678