Chemical Component Summary

NameD-MALATE
Synonyms(2R)-2-HYDROXYBUTANEDIOIC ACID; 2-HYDROXY-SUCCINIC ACID
Identifiers(2R)-2-oxidanylbutanedioic acid
FormulaC4 H6 O5
Molecular Weight134.087
TypeNON-POLYMER
Isomeric SMILESC([C@H](C(=O)O)O)C(=O)O
InChIInChI=1S/C4H6O5/c5-2(4(8)9)1-3(6)7/h2,5H,1H2,(H,6,7)(H,8,9)/t2-/m1/s1
InChIKeyBJEPYKJPYRNKOW-UWTATZPHSA-N

Chemical Details

Formal Charge0
Atom Count15
Chiral Atom Count1
Bond Count14
Aromatic Bond Count0

Drug Info: DrugBank

DrugBank IDDB03499 
NameD-Malic acid
Groups experimental
Synonyms
  • D-Malic acid
  • (+)-D-malic acid
  • (R)-2-hydroxybutanedioic acid
  • (R)-malic acid
CAS number636-61-3

Drug Targets

NameTarget SequencePharmacological ActionActions
NAD-dependent malic enzyme, mitochondrialMLSRLRVVSTTCTLACRHLHIKEKGKPLMLNPRTNKGMAFTLQERQMLGL...unknown
Citrate synthase, mitochondrialMALLTAAARLLGTKNASCLVLAARHASASSTNLKDILADLIPKEQARIKT...unknown
Circadian clock protein KaiBMSPFKKTYVLKLYVAGNTPNSVRALKMLKNILEQEFQGVYALKVIDVLKN...unknown
Fumarate hydratase class IIMNTVRSEKDSMGAIDVPADKLWGAQTQRSLEHFRISTEKMPTSLIHALAL...unknown
Malate synthase GMTDRVSVGNLRIARVLYDFVNNEALPGTDIDPDSFWAGVDKVVADLTPQN...unknown
View More
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682

Related Resource References

Resource NameReference
PubChem 92824
ChEMBL CHEMBL225986
ChEBI CHEBI:30796
CCDC/CSD CODCOO, XIYSOQ, NATDUK, HOZPOD