MGT

7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE

Find entries where: MGT

is present as a standalone ligand in 28 entries

as a non-polymer is covalently linked to polymer or other heterogen groups 4 entries

is present in a polymer sequence 1 entries

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Chemical Component Summary
Name	7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE
Identifiers	[[(2R,3S,4R,5R)-5-(2-amino-7-methyl-6-oxo-1,8-dihydropurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl] phosphono hydrogen phosphate
Formula	C₁₁ H₂₀ N₅ O₁₄ P₃
Molecular Weight	539.223
Type	NON-POLYMER
Isomeric SMILES	CN1CN(C2=C1C(=O)NC(=N2)N)[C@H]3[C@@H]([C@@H]([C@H](O3)CO[P@](=O)(O)O[P@](=O)(O)OP(=O)(O)O)O)O
InChI	InChI=1S/C11H20N5O14P3/c1-15-3-16(8-5(15)9(19)14-11(12)13-8)10-7(18)6(17)4(28-10)2-27-32(23,24)30-33(25,26)29-31(20,21)22/h4,6-7,10,17-18H,2-3H2,1H3,(H,23,24)(H,25,26)(H2,20,21,22)(H3,12,13,14,19)/t4-,6-,7-,10-/m1/s1
InChIKey	BUJQMJUTTBGELS-KQYNXXCUSA-N

Chemical Details
Formal Charge	0
Atom Count	53
Chiral Atom Count	6
Bond Count	55
Aromatic Bond Count	0

Drug Info: DrugBank

DrugBank ID	DB03358
Name	7-Methyl-7,8-dihydroguanosine 5'-(tetrahydrogen triphosphate)
Groups	experimental
Synonyms	7-Methyl-7,8-dihydroguanosine 5'-(tetrahydrogen triphosphate)

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase	MDVVSLDKPFMYFEEIDNELDYEPESANEVAKKLPYQGQLKLLLGELFFL...	unknown

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682