M7G

7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE

Find entries where: M7G

is present as a standalone ligand in 30 entries

as a non-polymer is covalently linked to polymer or other heterogen groups 3 entries

is present in a polymer sequence 17 entries

Find related ligands:

Similar Ligands (Stereospecific)

Similar Ligands (Quick Screen)

Toggle Hydrogen Toggle Labels

Chemical Component Summary
Name	7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE
Identifiers	[(2~{R},3~{S},4~{R},5~{R})-5-(2-azanyl-7-methyl-6-oxidanylidene-1~{H}-purin-7-ium-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl phosphono hydrogen phosphate
Formula	C₁₁ H₁₈ N₅ O₁₁ P₂
Molecular Weight	458.235
Type	NON-POLYMER
Isomeric SMILES	C[n+]1cn(c2c1C(=O)NC(=N2)N)[C@H]3[C@@H]([C@@H]([C@H](O3)CO[P@](=O)(O)OP(=O)(O)O)O)O
InChI	InChI=1S/C11H17N5O11P2/c1-15-3-16(8-5(15)9(19)14-11(12)13-8)10-7(18)6(17)4(26-10)2-25-29(23,24)27-28(20,21)22/h3-4,6-7,10,17-18H,2H2,1H3,(H5-,12,13,14,19,20,21,22,23,24)/p+1/t4-,6-,7-,10-/m1/s1
InChIKey	SBASPRRECYVBRF-KQYNXXCUSA-O

Chemical Details
Formal Charge	1
Atom Count	47
Chiral Atom Count	4
Bond Count	49
Aromatic Bond Count	5

Drug Info: DrugBank

DrugBank ID	DB01960
Name	7-methyl-7,8-dihydroguanosine-5'-diphosphate
Groups	experimental
Synonyms	7-methyl-7,8-dihydroguanosine-5'-diphosphate
CAS number	104809-16-7

Drug Targets

Name	Target Sequence	Pharmacological Action
m7GpppX diphosphatase	MADAAPQLGKRKRELDVEEAHAASTEEKEAGVGNGTCAPVRLPFSGFRLQ...	unknown
Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase	MDVVSLDKPFMYFEEIDNELDYEPESANEVAKKLPYQGQLKLLLGELFFL...	unknown
Eukaryotic translation initiation factor 4E	MATVEPETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKN...	unknown

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682