LW4

3-(1H-indol-3-yl)-4-[2-(4-methylpiperazin-1-yl)quinazolin-4-yl]-1H-pyrrole-2,5-dione


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Chemical Component Summary

Name3-(1H-indol-3-yl)-4-[2-(4-methylpiperazin-1-yl)quinazolin-4-yl]-1H-pyrrole-2,5-dione
Identifiers3-(1H-indol-3-yl)-4-[2-(4-methylpiperazin-1-yl)quinazolin-4-yl]pyrrole-2,5-dione
FormulaC25 H22 N6 O2
Molecular Weight438.481
TypeNON-POLYMER
Isomeric SMILESCN1CCN(CC1)c2nc3ccccc3c(n2)C4=C(C(=O)NC4=O)c5c[nH]c6c5cccc6
InChIInChI=1S/C25H22N6O2/c1-30-10-12-31(13-11-30)25-27-19-9-5-3-7-16(19)22(28-25)21-20(23(32)29-24(21)33)17-14-26-18-8-4-2-6-15(17)18/h2-9,14,26H,10-13H2,1H3,(H,29,32,33)
InChIKeyOAVGBZOFDPFGPJ-UHFFFAOYSA-N

Chemical Details

Formal Charge0
Atom Count55
Chiral Atom Count0
Bond Count60
Aromatic Bond Count21

Drug Info: DrugBank

DrugBank IDDB12369 
NameSotrastaurin
Groups investigational
DescriptionSotrastaurin has been used in trials studying the basic science and treatment of Uveal Melanoma, Richter Syndrome, Prolymphocytic Leukemia, Recurrent Mantle Cell Lymphoma, and Recurrent Small Lymphocytic Lymphoma, among others.
Synonyms
  • Sotrastaurinum
  • Sotrastaurina
  • Sotrastaurin acetate
  • Sotrastaurin
CategoriesHeterocyclic Compounds, Fused-Ring
CAS number425637-18-9

Related Resource References

Resource NameReference
Pharos CHEMBL565612
PubChem 10296883
ChEMBL CHEMBL565612
ChEBI CHEBI:90531