LNL

ALPHA-LINOLENIC ACID

Find entries where: LNL

is present as a standalone ligand in 5 entries

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Chemical Component Summary
Name	ALPHA-LINOLENIC ACID
Identifiers	(9Z)-octadeca-9,12,15-trienoic acid
Formula	C₁₈ H₃₀ O₂
Molecular Weight	278.43
Type	NON-POLYMER
Isomeric SMILES	CCC=CCC=CC\C=C/CCCCCCCC(=O)O
InChI	InChI=1S/C18H30O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h3-4,6-7,9-10H,2,5,8,11-17H2,1H3,(H,19,20)/b4-3-,7-6-,10-9-
InChIKey	DTOSIQBPPRVQHS-PDBXOOCHSA-N

Chemical Details
Formal Charge	0
Atom Count	50
Chiral Atom Count	0
Bond Count	49
Aromatic Bond Count	0

Drug Info: DrugBank

DrugBank ID	DB00132
Name	alpha-Linolenic acid
Groups	approved nutraceutical investigational
Description	Alpha-linolenic acid (ALA) is a polyunsaturated omega-3 fatty acid. It is a component of many common vegetable oils and is important to human nutrition.
Synonyms	9-cis,12-cis,15-cis-octadecatrienoic acid Linolenic acid 9,12,15-Octadecatrienoic acid ALA cis,cis,cis-9,12,15-Octadecatrienoic acid all-cis-9,12,15-Octadecatrienoic acid (Z,Z,Z)-9,12,15-octadecatrienoic acid (9Z,12Z,15Z)-Octadecatrienoic acid alpha-Linolenic acid α-linolenic acid (9,12,15)-linolenic acid cis-delta(9,12,15)-Octadecatrienoic acid
Brand Names	Huile D'onagre Vitamin E Folcaps Care One Advanced AM PM Flaxseed Oil Capsules UltimateCare ONE NF Bio-efa Borage Gla 90 Cap HemeNatal OB plus DHA Cavan One Folcaps Omega-3
Indication	For nutritional supplementation and for treating dietary shortage or imbalance.
Categories	Dietary Fats Dietary Fats, Unsaturated Dietary Supplements Fats Fatty Acids Fatty Acids, Essential Fatty Acids, Omega-3 Fatty Acids, Unsaturated Linolenic Acids Lipids Supplements
CAS number	463-40-1

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
Fatty acid desaturase 1	MAPDPVAAETAAQGPTPRYFTWDEVAQRSGCEERWLVIDRKVYNISEFTR...	unknown	ligand
Fatty acid desaturase 2	MGKGGNQGEGAAEREVSVPTFSWEEIQKHNLRTDRWLVIDRKVYNITKWS...	unknown	ligand
Transient receptor potential cation channel subfamily V member 1	MKKWSSTDLGAAADPLQKDTCPDPLDGDPNSRPPPAKPQLSTAKSRTRLF...	unknown	inhibitor
Peroxisome proliferator-activated receptor alpha	MVDTESPLCPLSPLEAGDLESPLSEEFLQEMGNIQEISQSIGEDSSGSFG...	unknown
Bile acid receptor	MVMQFQGLENPIQISPHCSCTPSGFFMEMMSMKPAKGVLTEQVAGPLGQN...	unknown	agonist
Peroxisome proliferator-activated receptor delta	MEQPQEEAPEVREEEEKEEVAEAEGAPELNGGPQHALPSSSYTDLSRSSS...	unknown
Peroxisome proliferator-activated receptor gamma	MGETLGDSPIDPESDSFTDTLSANISQEMTMVDTEMPFWPTNFGISSVDL...	unknown
Retinoic acid receptor RXR-alpha	MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSP...	unknown
Elongation of very long chain fatty acids protein 2	MEHLKAFDDEINAFLDNMFGPRDSRVRGWFMLDSYLPTFFLTVMYLLSIW...	unknown	substrate
Elongation of very long chain fatty acids protein 5	MEHFDASLSTYFKALLGPRDTRVKGWFLLDNYIPTFICSVIYLLIVWLGP...	unknown	substrate
Sodium/calcium exchanger 1	MYNMRRLSLSPTFSMGFHLLVTVSLLFSHVDHVIAETEMEGEGNETGECT...	unknown
Fatty acid-binding protein, brain	MVEAFCATWKLTNSQNFDEYMKALGVGFATRQVGNVTKPTVIISQEGDKV...	unknown
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Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682