L5G

7-methoxy-4-[(6-phenyl[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methoxy]quinoline

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is present as a standalone ligand in 1 entries

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Chemical Component Summary
Name	7-methoxy-4-[(6-phenyl[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methoxy]quinoline
Identifiers	7-methoxy-4-[(6-phenyl-[1,2,4]triazolo[5,4-f]pyridazin-3-yl)methoxy]quinoline
Formula	C₂₂ H₁₇ N₅ O₂
Molecular Weight	383.403
Type	NON-POLYMER
Isomeric SMILES	COc1ccc2c(ccnc2c1)OCc3nnc4n3nc(cc4)c5ccccc5
InChI	InChI=1S/C22H17N5O2/c1-28-16-7-8-17-19(13-16)23-12-11-20(17)29-14-22-25-24-21-10-9-18(26-27(21)22)15-5-3-2-4-6-15/h2-13H,14H2,1H3
InChIKey	HEAIZQNMNCHNFD-UHFFFAOYSA-N

Chemical Details
Formal Charge	0
Atom Count	46
Chiral Atom Count	0
Bond Count	50
Aromatic Bond Count	28

Drug Info: DrugBank

DrugBank ID	DB08079
Name	AMG-208
Groups	investigational
Description	AMG-208 has been used in trials studying the treatment of Cancer, Tumors, Oncology, Prostate Cancer, and Oncology Patients, among others.
Synonyms	AMG-208 7-methoxy-4-[(6-phenyl[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methoxy]quinoline
CAS number	1002304-34-8

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
Hepatocyte growth factor receptor	MKAPAVLAPGILVLLFTLVQRSNGECKEALAKSEMNVNMKYQLPNFTAET...	unknown	inhibitor

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682