KSA

K-252A

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is present as a standalone ligand in 5 entries

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Chemical Component Summary
Name	K-252A
Identifiers	n/a
Formula	C₂₇ H₂₁ N₃ O₅
Molecular Weight	467.473
Type	NON-POLYMER
Isomeric SMILES	C[C@@]12[C@](C[C@@H](O1)n3c4ccccc4c5c3c6n2c7ccccc7c6c8c5C(=O)NC8)(C(=O)OC)O
InChI	InChI=1S/C27H21N3O5/c1-26-27(33,25(32)34-2)11-18(35-26)29-16-9-5-3-7-13(16)20-21-15(12-28-24(21)31)19-14-8-4-6-10-17(14)30(26)23(19)22(20)29/h3-10,18,33H,11-12H2,1-2H3,(H,28,31)/t18-,26+,27+/m1/s1
InChIKey	KOZFSFOOLUUIGY-SOLYNIJKSA-N

Chemical Details
Formal Charge	0
Atom Count	56
Chiral Atom Count	3
Bond Count	63
Aromatic Bond Count	24

Drug Info: DrugBank

DrugBank ID	DB02152
Name	K-252a
Groups	experimental
Synonyms	K-252a
Categories	Alkaloids Enzyme Inhibitors Heterocyclic Compounds, Fused-Ring Indoles Indolizidines Indolizines Protein Kinase C, antagonists & inhibitors
CAS number	97161-97-2

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
Dual specificity mitogen-activated protein kinase kinase 1	MPKKKPTPIQLNPAPDGSAVNGTSSAETNLEALQKKLEELELDEQQRKRL...	unknown
Hepatocyte growth factor receptor	MKAPAVLAPGILVLLFTLVQRSNGECKEALAKSEMNVNMKYQLPNFTAET...	unknown

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682