ISN

ISATIN

Find entries where: ISN

is present as a standalone ligand in 7 entries

as a non-polymer is covalently linked to polymer or other heterogen groups 4 entries

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Chemical Component Summary
Name	ISATIN
Identifiers	1H-indole-2,3-dione
Formula	C₈ H₅ N O₂
Molecular Weight	147.131
Type	NON-POLYMER
Isomeric SMILES	c1ccc2c(c1)C(=O)C(=O)N2
InChI	InChI=1S/C8H5NO2/c10-7-5-3-1-2-4-6(5)9-8(7)11/h1-4H,(H,9,10,11)
InChIKey	JXDYKVIHCLTXOP-UHFFFAOYSA-N

Chemical Details
Formal Charge	0
Atom Count	16
Chiral Atom Count	0
Bond Count	17
Aromatic Bond Count	6

Drug Info: DrugBank

DrugBank ID	DB02095
Name	Isatin
Groups	experimental
Description	Isatin is an indole derivative first obtained by Erdman and Laurent in 1841 as an oxidation product of Indigo dye with nitric acid and chromic acids. The compound is found in many plants and Schiff bases of Isatin are have been investigated for pharmaceutical applications.
Synonyms	1H-indole-2,3-dione Isatin
Categories	Heterocyclic Compounds, Fused-Ring Indoles
CAS number	91-56-5

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
Amine oxidase [flavin-containing] B	MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQK...	unknown
Amine oxidase [flavin-containing] B	MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQK...	unknown	inhibitor

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682