Hyoscyamine is a tropane alkaloid and the levo-isomer of [atropine].[A228423] It is commonly extracted from plants in the _Solanaceae_ or nightshade family.[A228423] Research into the action of hyoscyamine in published literature dates back to 1826.[A228713] Hyoscyamine is used for a wide variety of treatments and therapeutics due to its antimuscarinic properties.[L31548,L31553] Although hyoscyamine is marketed in the United States, it is not FDA approved.[L31548,L31553]
Phenobarbital, Hyoscyamine Sulfate, Atropine Sulfate and Scopolamine Hydrobromide
Phenohytro
Ed-spaz
Hyoscyamine ER
PB Hyos
Utira-C
Uralgic
Uribel
Uramit Mb
Uretron D/S
HyoMax
Servira
Hyoscyamine Sulfate Drops
Levsin Drops 0.125mg/ml
Vilevev MB
Phenobarbital with Belladonna Alkaloids - Mint
Hyoscyamine sulfate
Urimar-T Caps
Me NaPhos MB Hyo 1
Hyosyne
B-Donna
Hyolev Mb
Uro-458
Belladonna Alkaloids with Phenobartbital
Phenazopyridine Plus
Hyophen
Donnatal Tab
Re-PB Hyos Elixir
Hyoscyamine S L
Urimar-T
Donnagel Liq
Darpaz
Hyoscyamine Sulfate Sl
Re-PB Hyos
Urin D/S
Phenobarbital With Belladonna Alkaloids
Hyoscyamine Sulfate TAB
Darcalma
Urogesic Blue
Indication
As a drug that is not FDA approved, hyscyamine has no official indications.[L31548,L31553] Intravenous hysocyamine has been used to reduce gastric motility, reduce pancreatic pain and secretions, to facilitate imaging of the gastrointestinal tract, treat anticholinesterase toxicity, treat certain cases of partial heart block, improve visualization of the kidneys, and for symptomatic relief of biliary and renal colic.[L31548] Intravenous hyoscyamine is also used pre-operatively to reduce secretions of the mouth and respiratory tract to facilitate intubation.[L31548] Oral hyoscyamine is used to treat functional intestinal disorders, for symptomatic relief of biliary and renal colic, and symptomatic relief of acute rhinitis.[L31553]
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison
T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS.
Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682