Acetohydroxamic Acid, a synthetic drug derived from hydroxylamine and ethyl acetate, is similar in structure to urea. In the urine, it acts as an antagonist of the bacterial enzyme urease. Acetohydroxamic Acid has no direct antimicrobial action and does not acidify urine directly. It is used, in addition to antibiotics or medical procedures, to treat chronic urea-splitting urinary infections.
Synonyms
Acetohydroximic acid
Acetylhydroxamic acid
Methylhydroxamic acid
Acetyl hydroxyamino
Acethydroxamsaeure
Acetohydroxamate
Acido acetohidroxamico
N-Acetylhydroxylamine
N-Hydroxyacetamide
Acetic acid, oxime
Acidum acetohydroxamicum
Acide acetohydroxamique
Acetohydroxamic acid
AHA
N-Acetyl hydroxyacetamide
Cetohyroxamic acid
Brand Names
Lithostat
Indication
Used, in addition to antibiotics or medical procedures, to treat chronic urea-splitting urinary infections.
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison
T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS.
Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682
