GAX

1-{3-[(4-pyridin-2-ylpiperazin-1-yl)sulfonyl]phenyl}-3-(1,3-thiazol-2-yl)urea

Find entries where: GAX

is present as a standalone ligand in 3 entries

Find related ligands:

Chemical Component Summary
Name	1-{3-[(4-pyridin-2-ylpiperazin-1-yl)sulfonyl]phenyl}-3-(1,3-thiazol-2-yl)urea
Identifiers	3-[3-(4-pyridin-2-ylpiperazin-1-yl)sulfonylphenyl]-1-(1,3-thiazol-2-yl)urea
Formula	C₁₉ H₂₀ N₆ O₃ S₂
Molecular Weight	444.531
Type	NON-POLYMER
Isomeric SMILES	c1ccnc(c1)N2CCN(CC2)S(=O)(=O)c3cccc(c3)NC(=O)Nc4nccs4
InChI	InChI=1S/C19H20N6O3S2/c26-18(23-19-21-8-13-29-19)22-15-4-3-5-16(14-15)30(27,28)25-11-9-24(10-12-25)17-6-1-2-7-20-17/h1-8,13-14H,9-12H2,(H2,21,22,23,26)
InChIKey	NJPVZSIGDRLLTD-UHFFFAOYSA-N

Chemical Details
Formal Charge	0
Atom Count	50
Chiral Atom Count	0
Bond Count	53
Aromatic Bond Count	17

Drug Info: DrugBank

DrugBank ID	DB07817
Name	1-{3-[(4-pyridin-2-ylpiperazin-1-yl)sulfonyl]phenyl}-3-(1,3-thiazol-2-yl)urea
Groups	experimental
Synonyms	1-{3-[(4-pyridin-2-ylpiperazin-1-yl)sulfonyl]phenyl}-3-(1,3-thiazol-2-yl)urea

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
Phenylalanine--tRNA ligase alpha subunit	MTQNDSMAELKQQALVDINEAQNERELQDVKVKYLGKKGSVSGLMKNMKD...	unknown
Phenylalanine--tRNA ligase beta subunit	MLISNEWLKDYVDAGVKVEDLAERITRTGIEVDDMIDYSKDIKNLVVGYI...	unknown

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682