EDR

EDROPHONIUM ION

Find entries where: EDR

is present as a standalone ligand in 2 entries

Find related ligands:

Chemical Component Summary
Name	EDROPHONIUM ION
Identifiers	ethyl-(3-hydroxyphenyl)-dimethyl-azanium
Formula	C₁₀ H₁₆ N O
Molecular Weight	166.24
Type	NON-POLYMER
Isomeric SMILES	CC[N+](C)(C)c1cccc(c1)O
InChI	InChI=1S/C10H15NO/c1-4-11(2,3)9-6-5-7-10(12)8-9/h5-8H,4H2,1-3H3/p+1
InChIKey	VWLHWLSRQJQWRG-UHFFFAOYSA-O

Chemical Details
Formal Charge	1
Atom Count	28
Chiral Atom Count	0
Bond Count	28
Aromatic Bond Count	6

Drug Info: DrugBank

DrugBank ID	DB01010
Name	Edrophonium
Groups	approved
Description	A rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. It has also been used as an antidote to curare principles.
Synonyms	Edrophonium bromide Edrophonium chloride 3-hydroxy-N,N-dimethyl-N-ethylanilinium N-ethyl-3-hydroxy-N,N-dimethylanilinium Ethyl-(3-hydroxy-phenyl)-dimethyl-ammonium Edrophonium N-ethyl-3-hydroxy-N,N-dimethylbenzenaminium Edrophonium cation (3-hydroxyphenyl)dimethylethylammonium Edrophonium ion
Brand Names	Tensilon Enlon Liq IV 10mg/ml Enlon 10mg/ml Enlon-Plus Enlon Plus Enlon
Indication	For the differential diagnosis of myasthenia gravis and as an adjunct in the evaluation of treatment requirements in this disease. It may also be used for evaluating emergency treatment in myasthenic crises.
Categories	Amines Antidotes Cholinergic Agents Cholinesterase Inhibitors Compounds used in a research, industrial, or household setting Diagnostic Agents Drugs that are Mainly Renally Excreted Enzyme Inhibitors Neurotransmitter Agents Onium Compounds Phenylammonium Compounds Protective Agents Quaternary Ammonium Compounds
ATC-Code	V04CX07
CAS number	312-48-1

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
Cholinesterase	MHSKVTIICIRFLFWFLLLCMLIGKSHTEDDIIIATKNGKVRGMNLTVFG...	unknown	inhibitor
Acetylcholinesterase	MRPPQCLLHTPSLASPLLLLLLWLLGGGVGAEGREDAELLVTVRGGRLRG...	unknown	inhibitor

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682