E0G

4-[6,6-dimethyl-4-oxidanylidene-3-(trifluoromethyl)-5,7-dihydroindazol-1-yl]-2-[(4-oxidanylcyclohexyl)amino]benzamide


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Chemical Component Summary

Name4-[6,6-dimethyl-4-oxidanylidene-3-(trifluoromethyl)-5,7-dihydroindazol-1-yl]-2-[(4-oxidanylcyclohexyl)amino]benzamide
Identifiers4-[6,6-dimethyl-4-oxidanylidene-3-(trifluoromethyl)-5,7-dihydroindazol-1-yl]-2-[(4-oxidanylcyclohexyl)amino]benzamide
FormulaC23 H27 F3 N4 O3
Molecular Weight464.481
TypeNON-POLYMER
Isomeric SMILESCC1(Cc2c(c(nn2c3ccc(c(c3)NC4CCC(CC4)O)C(=O)N)C(F)(F)F)C(=O)C1)C
InChIInChI=1S/C23H27F3N4O3/c1-22(2)10-17-19(18(32)11-22)20(23(24,25)26)29-30(17)13-5-8-15(21(27)33)16(9-13)28-12-3-6-14(31)7-4-12/h5,8-9,12,14,28,31H,3-4,6-7,10-11H2,1-2H3,(H2,27,33)/t12-,14-
InChIKeyZFVRYNYOPQZKDG-MQMHXKEQSA-N

Chemical Details

Formal Charge0
Atom Count60
Chiral Atom Count0
Bond Count63
Aromatic Bond Count11

Drug Info: DrugBank

DrugBank IDDB17055 
NameSNX-2112
Groups investigational
DescriptionSNX-2112 is a heat shock protein 90 (Hsp90) inhibitor.[A253137]
Synonyms
  • SNX-2112
  • Benzamide, 2-((trans-4-hydroxycyclohexyl)amino)-4-(4,5,6,7-tetrahydro-6,6-dimethyl-4-oxo-3-(trifluoromethyl)-1h-indazol-1-yl)-
Categories
  • Heterocyclic Compounds, Fused-Ring
  • HSP90 Heat-Shock Proteins, antagonists & inhibitors
CAS number908112-43-6