Chemical Component Summary

NameDEOXYURIDINE-5'-TRIPHOSPHATE
Identifiers[(2R,3S,5R)-5-(2,4-dioxopyrimidin-1-yl)-3-hydroxy-oxolan-2-yl]methyl (hydroxy-phosphonooxy-phosphoryl) hydrogen phosphate
FormulaC9 H15 N2 O14 P3
Molecular Weight468.142
TypeNON-POLYMER
Isomeric SMILESC1[C@@H]([C@H](O[C@H]1N2C=CC(=O)NC2=O)CO[P@@](=O)(O)O[P@](=O)(O)OP(=O)(O)O)O
InChIInChI=1S/C9H15N2O14P3/c12-5-3-8(11-2-1-7(13)10-9(11)14)23-6(5)4-22-27(18,19)25-28(20,21)24-26(15,16)17/h1-2,5-6,8,12H,3-4H2,(H,18,19)(H,20,21)(H,10,13,14)(H2,15,16,17)/t5-,6+,8+/m0/s1
InChIKeyAHCYMLUZIRLXAA-SHYZEUOFSA-N

Chemical Details

Formal Charge0
Atom Count43
Chiral Atom Count5
Bond Count44
Aromatic Bond Count0

Drug Info: DrugBank

DrugBank IDDB02333 
NameDeoxyuridine-5'-Triphosphate
Groups experimental
SynonymsDeoxyuridine-5'-Triphosphate

Drug Targets

NameTarget SequencePharmacological ActionActions
Septum formation protein MafMTKPLILASQSPRRKELLDLLQLPYSIIVSEVEEKLNRNFSPEENVQWLA...unknown
Pol polyproteinKEFGKLEGGASCSPSESNAASSNAICTSNGGETIGFVNYNKVGTTTTLEK...unknown
Deoxycytidine triphosphate deaminaseMRLCDRDIEAWLDEGRLSINPRPPVERINGATVDVRLGNKFRTFRGHTAA...unknown
Deoxyuridine 5'-triphosphate nucleotidohydrolaseMSTTLAIVRLDPGLPLPSRAHDGDAGVDLYSAEDVELAPGRRALVRTGVA...unknown
Deoxyuridine 5'-triphosphate nucleotidohydrolaseMKKIDVKILDPRVGKEFPLPTYATSGSAGLDLRACLNDAVELAPGDTTLV...unknown
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682

Related Resource References

Resource NameReference
PubChem 65070
ChEMBL CHEMBL374361
ChEBI CHEBI:17625