DTR

D-TRYPTOPHAN


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Chemical Component Summary

NameD-TRYPTOPHAN
Identifiers(2R)-2-amino-3-(1H-indol-3-yl)propanoic acid
FormulaC11 H12 N2 O2
Molecular Weight204.225
TypeD-PEPTIDE LINKING
Isomeric SMILESc1ccc2c(c1)c(c[nH]2)C[C@H](C(=O)O)N
InChIInChI=1S/C11H12N2O2/c12-9(11(14)15)5-7-6-13-10-4-2-1-3-8(7)10/h1-4,6,9,13H,5,12H2,(H,14,15)/t9-/m1/s1
InChIKeyQIVBCDIJIAJPQS-SECBINFHSA-N

Chemical Details

Formal Charge0
Atom Count27
Chiral Atom Count1
Bond Count28
Aromatic Bond Count10

Drug Info: DrugBank

DrugBank IDDB03225 
NameD-Tryptophan
Groups experimental
DescriptionTryptophan is one of the 20 standard amino acids, as well as an essential amino acid in the human diet. It is encoded in the standard genetic code as the codon UGG. The D-stereoisomer is occasionally found in naturally produced peptides (for example, the marine venom peptide contryphan). The distinguishing structural characteristic of tryptophan is that it contains an indole functional group. It is an essential amino acid as defined by its growth effects on rats.
Synonyms
  • (R)-tryptophan
  • D-Tryptophan
  • DTR
  • (2R)-2-amino-3-(1H-indol-3-yl)propanoic acid
CAS number153-94-6

Drug Targets

NameTarget SequencePharmacological ActionActions
D-amino-acid oxidaseMRVVVIGAGVIGLSTALCIHERYHSVLQPLDIKVYADRFTPLTTTDVAAG...unknown
Monocarboxylate transporter 10MVLSQEEPDSARGTSEAQPLGPAPTGAAPPPGPGPSDSPEAAVEKVEVEL...unknowninhibitor
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682

Related Resource References

Resource NameReference
PubChem 9060, 6923517
ChEMBL CHEMBL292303
ChEBI CHEBI:57719, CHEBI:16296
CCDC/CSD TAJSUV, QQQBTP02, RODSOU, IMENAR, TAKKAU, TRYPTB, TRYPTF10, XAMCEW, BEBCAP, TPTPCM, TRYPTC, QQQBTP05
COD 4517355