CNY

13,15-DIAMINO-2-(AMINOMETHYL)-3,4,9,12-TETRAHYDROXYHEXADECAHYDRO-2H-7,10-EPOXYPYRANO[2,3-B][1,10,4]BENZODIOXAZACYCLODODECIN-8-YL 2,6-DIAMINO-2,6-DIDEOXYHEXOPYRANOSIDE

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Chemical Component Summary
Name	13,15-DIAMINO-2-(AMINOMETHYL)-3,4,9,12-TETRAHYDROXYHEXADECAHYDRO-2H-7,10-EPOXYPYRANO[2,3-B][1,10,4]BENZODIOXAZACYCLODODECIN-8-YL 2,6-DIAMINO-2,6-DIDEOXYHEXOPYRANOSIDE
Synonyms	CYCLIC NEOMYCIN
Identifiers	n/a
Formula	C₂₃ H₄₄ N₆ O₁₂
Molecular Weight	596.628
Type	NON-POLYMER
Isomeric SMILES	C1[C@H]([C@@H]([C@@H]2[C@@H]([C@H]1N)O[C@@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CN)O)O)NC[C@@H]4[C@H]([C@H]([C@@H](O4)O2)O)O[C@@H]5[C@@H]([C@H]([C@@H]([C@@H](O5)CN)O)O)N)O)N
InChI	InChI=1S/C23H44N6O12/c24-2-7-13(31)15(33)10(28)21(36-7)40-19-9-4-29-11-16(34)14(32)8(3-25)37-22(11)39-18-6(27)1-5(26)12(30)20(18)41-23(38-9)17(19)35/h5-23,29-35H,1-4,24-28H2/t5-,6+,7+,8-,9-,10-,11-,12+,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23+/m1/s1
InChIKey	DXIORKRGAWCDSD-LSWIJEOBSA-N

Chemical Details
Formal Charge	0
Atom Count	85
Chiral Atom Count	19
Bond Count	89
Aromatic Bond Count	0

Drug Info: DrugBank

DrugBank ID	DB00994
Name	Neomycin
Groups	vet_approved approved
Description	Neomycin is a broad-spectrum aminoglycoside antibiotic drug that is derived from the metabolic products of _Streptomyces fradiae_.[L11979] Neomycin is a complex comprised of three components, neomycin A, B, and C.[A191529] Neomycin B, also known as [framycetin], is the most active component of the complex and neomycin C is the isomer of neomycin B, making these two stereoisomers the active components of neomycin.[A175042,A191529] Neomycin A, or [neamine], is a moiety that conjoins two molecules of neomycin B and C together.[A175042] Neomycin is active against both gram-positive and gram-negative organisms and mediates its pharmacological action by binding to bacterial ribosomes and inhibiting protein synthesis, which is crucial for the survival of bacteria.[L11985] Neomycin sulfate is the most common form for pharmaceutical preparations; because the compound is a complex, the amount of neomycin in products is measured in units.[A191529] Neomycin sulfate as monotherapy is available in an oral solution for adjunct use in the treatment of hepatic coma.[L11979] It is also used in combination with [polymyxin B] sulfates and [hydrocortisone] in otic suspensions for use in the treatment of bacterial infections in the external auditory canal, including infections caused by medical procedures in the ear.[L10532] Neomycin is also used in combination with [polymyxin B] sulfates and [dexamethasone] in ophthalmic preparations for use in the treatment of inflammatory conditions and infections in the eye.[L10716] Neomycin is also available in over-the-counter topical products to prevent minor skin infections.
Synonyms	Vonamycin Neomicina Kaomycine Neomycin palmitate Neomycin sulfate Fradiomycin Neomycin
Brand Names	Rite Aid Pharmacy Antibiotic With Pain Relief 50 Person ANSI Neosporin Kids Plus Pain Relief DG Health Triple Antibiotic Equate First Aid Antibiotic Pain Relieving Odan-trol Fulton Street Market Triple Antibiotic Original Strength Sheffield Triple Antibiotic GENUINE FIRST AID Emergency Preparedness Contains 167 PIECES HARDCASE Neo-poly-bac Hydro Xpect Triple Antibiotic 4248 First Aid Kit 4355 First Aid Kit Neo-medrol 4229 First Aid Kit 4109 First Aid Kit FIRST AID Contains 1000 PIECES Good Neighbor Pharmacy Triple Antibiotic Plus Pain Relief 4358 First Aid Kit Triple Antibiotic and Pain Relief Triple Antibiotic Plus Maximum Strength Equaline Antibiotic Plus Pain Relief Family Care Triple Antibiotic Plus Pain Relief Good Neighbor Pharmacy Triple Antibiotic FAK Large Office First Aid kit 4090 First Aid Kit Major Triple Antibiotic 4363 First Aid Kit 4298 First Aid Kit Otizol HC Liq Neosporin Plus Pain Relief First Aid Antibiotic Pain Relieving For Kids CVS First Aid Kit Neosporin Irrigating Solution Tribiotic 4263 First Aid Kit TheraPlusPlus Plus 4110 First Aid Kit Triastem Topical Antibiotic Up and Up Antibiotic Triple Antibiotic Plus Pain Relief Medpride First Aid Bacitracin Zinc, Neomycin Sulfate and Polymyxin B Sulfate Neo-cortef Eye Ear Drops Sterile Suspension Aminoderm Poudre The New Parent First Aid Ori-power 4269 First Aid Kit Baclezene Teva-triacomb Neosporin Plus Pain Relief Clubtray 4222 First Aid Kit 4400 First Aid Kit ARC FIRST AID Contains 303 PIECES HARDCASE Triple antibiotic and pain relief Triple Antibiotic GRX Exchange Select First Aid Triple Anitbiotic Pain Relieving Kenacomb Ont Triple Antibiotic CVS Easy Care First Aid Kit - Sports and Travel Antibiotic Ointment Neo-poly-bac First Aid Antibiotic and Pain Relief 4097 First Aid Kit Bacitracin Zinc, Neomycin Sulfate, and Polymyxin B Sulfate Johnson and Johnson First Aid Travel Ready 80 CT 4221 First Aid Kit FIRST AID Contains 303 PIECES HARDCASE 4292 First Aid Kit 4215 First Aid Kit 4141 First Aid Kit Green Guard Triple Antibiotic Emergency Preparedness Welly First Aid Kit 4120 First Aid Kit Ready America First Aid Outdoor- 107 Pieces health and .beyond Triple Antibiotic Antibiotic Application Roosin Triple Antibiotic meijer Triple Antibiotic 4284 First Aid Kit Small Cuts and Burns Neo-medrol Acne Lotion Bacitracin Mountain Series Weekender Medical Careone Triple Antibiotic Quality Choice Triple Antibiotic FIRST AID Contains 404 PIECES Large ANSI First Aid Kit Viaderm Kc Crm 4305 First Aid Kit 4084 First Aid Kit Harris Teeter Triple Antibioitic Triple Antibiotic Maximum Strength 4254 First Aid Kit Shopko Antibiotic Plus Pain Relief First Aid Antibiotic Roosin Neomycin Antibiotic Sunmark Antibiotic Plus Pain Relief Walgreens Kids Multi-Antibiotic with Pain Relief Cream OP Triple Antibiotic Welly Human Repair Kit Neosporin Ophthalmic Ointment Neomycin and Polymyxin B Sulfates, Bacitracin Zinc, and Hydrocortisone 4339 First Aid Kit ARC FIRST AID Contains 303 PIECES 4212 First Aid Kit MAKESENSE First Aid AVON HeXashield Triple Antibiotic with Pain Relief CVS Health Triple Antibiotic Schein Triple Antibiotic Neo-polycin Good Sense First Aid Antibiotic Kenacomb Mild Ointment Pentrexcilina Triple Antibiotic 4306 First Aid Kit Premier Value Max Strength Antibiotic plus pain relief Kenacomb Mild Cream GFA First Aid 36 Unit Metal Case Redicare Triple Antibiotic First Aid 4083 First Aid Kit 4152 First Aid Kit 4289 First Aid Kit 4314 First Aid Kit Antibiotic plus Pain Relief Standard ANSI First Aid Travel Savvy First Aid Triple Antibiotic Equate First Aid Antibiotic Plus Pain Relief Basic Care First Aid Antibiotic Family Care Triple Antibiotic Pain Relief Pentrexcilina Triple Antibiotic Plus Pain Relief 4319 First Aid Kit Publix antibiotic plus Pain Relief Western Family Antibiotic Plus Pain Relief Cambison 4101 First Aid Kit 4185 First Aid Kit Fonow Leader Triple Antibiotic and Pain Relief Drs. pharmacy triple antibiotic GFA First Aid 75 Person Metal Case Sandoz Cortimyxin meijer Triple Antibiotic plus Pain Relief 4210 First Aid Kit Medi-first 4049 First Aid Kit Triple antibiotic and pain itch scar Walgreens Maximum Strength Triple Antibiotic With Pain Relief First Aid Value Pack - 77 Pieces GLINT TRIPLE ANTIBIOTIC First Aid Equaline First Aid Antibiotic Neo Polycin HC CVS All Purpose First Aid Kit Antibiotic Original Strength Bi-Mart Triple Antibiotic Family Wellness Pain Scar Itch 4232 First Aid Kit Welly Excursion First Aid Kit PS - 2895 Triple Antibiotic , 0.5g AK-Trol Sx1 Medicated Post-Operative System WalgreensTriple Antibiotic 4361 First Aid Kit Bacitracin Zinc, Polymyxin B Sulfate, and Neomycin Sulfate 4310 First Aid Kit 4115 First Aid Kit 4117 First Aid Kit 4373 First Aid Kit Basic Care First Aid Antibiotic Plus Pain Relief Genuine Triple Antibiotic 4336 First Aid Kit DG Health Antibiotic Family Care Triple Antibiotic Welly Bravery Triple Antibiotic with Pain Relief 4195 First Aid Kit Multi Action Welly Infection Fighter Western Family Triple Antibiotic plus Pain Relief Antibiotic Maximum Strength Easy Care First Aid Chest - Home and Workshop North Triple Antibiotic Smart Sense triple antibitotic plus pain relief 4045 First Aid Kit Leader Triple Antibiotic Mycifradin Sulfate Oral Solution 4240 First Aid Kit 4349 First Aid Kit 4371 First Aid Kit Atopalm First Aid Triple Antibiotic plus Pain Relief Casporyn HC CAREONE Antibiotic Plus Pain Relief Tripleantibioticointmentandpainrelief Equate First Aid Antibiotic Triple Antibiotic Proctosone Sup Neosporin Eye-ear Solution Leader Triple antibiotic and pain relief Welly Adventure First Aid Kit Shoprite Triple Antibiotic Select Medical Products Triple Antibiotic Welly Bravery Triple Antibiotic Cortisporin Ophthalmic 4272 First Aid Kit 4315 First Aid Kit Dr Bells Pomade Neosporin Plus Lidocaine 4250 First Aid Kit Neosporin Ointment ProcureTriple Antibiotic Triple Antibiotic Good Sense Triple Antibiotic and Pain Relief 4220 First Aid Kit Ready America First Aid Pocket - 33 Pieces Adventure Medical Kits 1-2 Person National Ski Patrol First Aid Poly-pred Diphen 4113 First Aid Kit Cardinal Health First Aid Antibiotic First Aid Pocket Pack - 40 Pieces Up and Up multi action antibiotic CVS Health All Purpose Kit 4255 First Aid Kit Welly Bravery First Aid Kit 4338 First Aid Kit Good Sense Triple Antibiotic Quality Choice Triple Antibiotic Plus Pain Reliever 4281 First Aid Kit 4370 First Aid Kit CVS Health Sports Kit Water-Jel 3-in-1 Antibiotic Neo-Fradin CVS Cuts and Scrapes Refill Pack Cortisporin TC 4082 First Aid Kit Equaline Triple Antibiotic Plus Omnisporin Dg Health Triple Antibiotic 4376 First Aid Kit 4353 First Aid Kit 4017 First Aid Kit Neo-polycin HC Walgreens Triple Antibiotic 25 Person ANSI Drs. Pharmacy Triple Antibiotic Plus First Aid Only Neomycin Antibiotic 4387 First Aid Kit ANCALIMA First Aid 4252 First Aid Kit CVS Triple Antibiotic Neo-cortef 1% Ointment Wound Healer Publix antibiotic plus pain relief 4271 First Aid Kit Triple Antibiotic plus pain relief Adventure First Aid .5 Tin Paraid Triple Antibiotic 10 Person ANSI Cortisporin-TC Western Family Triple Antibiotic 4316 First Aid Kit 4367 First Aid Kit 4392 First Aid Kit Neomycin and Polymyxin B Sulfates and Hydrocortisone Otic Suspension TopCare Triple Antibiotic Plus Pain Relief Neomycin Sulfate, Polymyxin B Sulfate and Dexamethasone Our Family Triple Antibiotic Repara Triple Antibiotic 4351 First Aid Kit Biotic-Plus Family Wellness Triple Antibiotic Plus Pain Relief 4067 First Aid Kit 4068 First Aid Kit 4108 First Aid Kit Medi-First Dioptrol Suspension 4317 First Aid Kit 4065 First Aid Kit Multi Antibiotic with Pain Relief Maximum Strength 4042 First Aid Kit 4241 First Aid Kit Neotopic Ointment 4197 First Aid Kit 4264 First Aid Kit Adventure Medical Kits 1-4 Person First Aid Pomada Sulfa First Aid Antibiotic Neosporin G.U. American Red Cross First Aid Kit Neomycin Sulfate, Polymyxin B Sulfate and Bacitracin Zinc Kenacomb Ointment Family wellness WinCo Original Strength Triple Antibiotic 4167 First Aid Kit Medi-First Plus Triple Antibiotic Shopko Triple Antibiotic Acme Home/Office/Auto Kit Live Better Triple Antibiotic 4323 First Aid Kit Statrol Walgreens Multi-Antibiotic with Pain Relief Cream OLP Triple Antibiotic 4081 First Aid Kit 4201 First Aid Kit 4383 First Aid Kit Sunmark Triple Antibiotic Plus Pain Relief 4088 First Aid Kit CVS Health Triple Antibiotic with Pain Relief Double Antibiotic Plus Pain Relief Maximum Strength Premier Value Triple Antibiotic Cuadriderma Myciguent Ointment Lucky SuperSoft First Aid Neomycin Sulfate Adventure Medical Kits 1-2 Person First Aid 4116 First Aid Kit Topcare Triple Antibiotic 4198 First Aid Kit Leader Triple Antibiotic Plus Neosporin Good Neighbor Pharmacy Antibiotic and Pain Relief Neomycin and Polymyxin B Sulfates and Dexamethasone Equaline Triple Antibiotic Family Wellness Plus Pain Relief 4231First Aid Kit Natureplex Antibiotic plus Pain Neomycin Polymyxin B Sulfates and Dexamethasone Optimyxin Plus 4360 First Aid Kit Topcare Antibiotic Antibiotic Plus Pain Relief Ecolab Triple Antibiotic Good Neighbor Pharmacy First Aid Neosporin Antibiotic Cream 4219 First Aid Kit 4288 First Aid Kit 4384 First Aid Kit 4099 First Aid Kit Berkley and Jensen Triple Antibiotic 4151 First Aid Kit 4342 First Aid Kit Methedex Neomycin and Polymyxin B Sulfates and Bacitracin Zinc with Hydrocortisone Acetate Neomycin and Polymyxin B Sulfates TheraCare First Aid Triple Antibiotic 4218 First Aid Kit First Aid Triple Antibiotic Pain and Scar Premier Value Antibiotic Plus Pain Relief Welly Quick Fix Kit 4239 First Aid Kit Viaderm Kc Ont 4356 First Aid Kit 4364 First Aid Kit Kenacomb Cream No-SCAR Oint. Triple Antibiotic and Burn Relief OLP Triple Antibiotic Plus 4106 First Aid Kit 4230 First Aid Kit DAYMARK FAK-35 First Aid Care Science Essential First Aid Neo-cortef 0.5% Ointment 4381 First Aid Kit Neomycin and Polymyxin B sulfates, Bacitracin zinc 4287 First Aid Kit Coly-Mycin S Kit Breakroom Office First Aid Medi-First Triple Antibiotic Triple Antibiotic First Aid 4044 First Aid Kit 4199 First Aid Kit Quality Choice Maximum Strength Triple Antibiotic Triple Antibiotic HC 4166 First Aid Kit 4155 First Aid Kit 4279 First Aid Kit Penimixcina LEADER Triple Antibiotic LiveBetter Antibiotic Plus Pain Relief 4196 First Aid Kit S-Oint TRIPLE ANTIBIOTIC Smart Sense antibiotic plus pain relief GFA First Aid 16 Unit Metal Case 4274 First Aid Kit Synalar Bi-otic Solution Exchange Select triple antibiotic Tribioticlc Lc Lc Antibiotic and Pain Relief Maximum Strength Meijer Triple Antibiotic Plus 4382 First Aid Kit Childrens Double Antibiotic with Pain Relief Refill 2 Triple Antibiotic Ointment 4291 First Aid Kit 4249 First Aid Kit Johnson and Johnson All Purpose First Aid Kit Shopko Triple Antibiotic Plus ProCoMycin Neomycin and Polymyxin B Sulfates, Bacitracin Zinc and Hydrocortisone Smart Sense Triple Antibiotic ARC FIRST AID Contains 404 PIECES Healthy Accents Triple Antibiotic 4064 First Aid Kit Astonea First Aid 4168 First Aid Kit 4303 First Aid Kit CVS Health Healing on the Go Kit 4393 First Aid Kit 4390 First Aid Kit First Aid Triple Antibiotic 4104 First Aid Kit FIRST AID Contains 303 PIECES ReCellTis T.R.U.E. Test Thin-Layer Rapid Use Patch Test 4114 First Aid Kit Triple Antibiotic with Pain Relief 4266 First Aid Kit Lidecomb Cream Signature Care Triple Antibiotic Smart Sense Antibiotic Maximum Strength Formucare Triple Antibiotic Original Strength 4050 First Aid Kit First Aid Only Triple Antibiotic Healthy Accents triple antibiotic CAREONE Triple Antibiotic 4253 First Aid Kit Antibiotic, Pain and Scar Procure Triple Antibiotic Cream plus Active Manuka Honey First Aid Antibiotic plus Burn Relief Thompson Triple Antibiotic Neo/Poly-B/Dex Ophth Oint Water-Jel Neomycin Antibiotic ACME Small Cuts and Burns CVS Health Medication and Topical Refill Pouch Circle K Triple Antibiotic 4330 First Aid Kit Cicatrin Powder GoodSense Antibiotic plus Pain Relief Maximum Strength Triple Antibiotic Kit Large Office First Aid Easy Care First Aid Triple Antibiotic 4388 First Aid Kit 4056 First Aid Kit Equate Antibiotic Plus Pain Relief CareALL Triple Antibiotic Caring Mills Triple Antibiotic EQUATE Triple Antibiotic Aerosoothe 4304 First Aid Kit Genuine First Aid - Auto First Aid 4150 First Aid Kit 4282 First Aid Kit Natureplex Antibiotic Plus Pain, Itch, Scar Relief Travel Savvy Triple Antibiotic Family Wellness Original TheraCare Triple Antibiotic Pain Relief Equaline Antibiotic Plus Pain Relief for Kids Good Neighbor Pharmacy Emergency Preparedness and First Aid Contains 167 Pieces Sheffield Triple Antibiotic Plus Pain Relief GFA First Aid 24 Unit Metal Case NEOSPORIN Plus BURN RELIEF Harris Teeter Triple Antibiotic Plus Pain Relief Zee 3-in-One First Aid Antibiotic 4256 First Aid Kit Meijer Antibiotic Plus Pain Relief Antibiotic Ear (Neo/Polym/HC) BLUE ACME SLEEVE FIRST AID Contains 1000 PIECES 4066 First Aid Kit Easy Care First Aid - All Purpose Lincoln 4200 First Aid Kit Neodecadron Eye Ear Soln 0.1% Triple Antibiotic Extra Strength MediChoice Triple Antibiotic WinCo Maximum Strength Triple Antibiotic Neosporin Plus Pain Relief Neo To Go First Aid Antibiotic Pain Relieving Vitacilina First Aid Antibiotic 4399 First Aid Kit Theraderm Cream 4211 First Aid Kit 4119 First Aid Kit 4242 First Aid Kit Neomycin and Polymyxin B Sulfates and Hydrocortisone Up and Up First Aid Antibiotic Pain Relieving WELL AT WALG TRIPLE ANTIBIOTIC Well at Walgreens 4346 First Aid Kit 4138 First Aid Kit Antibiotic Plus Pain Relief Maximum Strength NATUREPLEX ANTIBIOTIC plus PAIN RELIEF Maxitrol Diosporin Ointment ShopRite Triple Antibiotic Antibiotic and pain relief maximum strength Shopko Triple Antibiotic plus Pain Relief 4085 First Aid Kit ReCellTis Wound Cream Cortomycin Atopalm First Aid Triple Antibiotic Genuine First Aid Industrial First Aid 4402 First Aid Kit 4100 First Aid Kit Signature Care First Aid Antibiotic Careone Original Strength Triple Antibiotic FAK Care4 Bus and School Yellow ORM D NEOMYCIN and POLYMYXIN B SULFATES and HYDROCORTISONE Neomycin and polymyxin B sulfates and bacitracin zinc Market Basket First Aid Triple Antibiotic Neosporin Original Triple Antibiotic First Aid Antibiotic GFA First Aid Family Care Antibiotic H E Buddy Antibiotic Maximum Strength Plus Pain Relief 4389 First Aid Kit CareALL Triple Antibiotic plus Pain Relief Dioptrol Ointment 7 Select First Aid Triple Antibiotic Curad Maximum Strength Triple Antibiotic 4051 First Aid Kit 4235 First Aid Kit 4089 First Aid Kit Live Better Triple Antibiotic plus Pain Relief Vitacilina Neomycin Sulfate First Aid Antibiotic 4395 First Aid Kit 4087 First Aid Kit Sunmark Triple Antibiotic 4125 First Aid Kit 4344 First Aid Kit Mecomb Crm 0.1% Madecassol Welly Superhero Supplies Kit 4352 First Aid Kit 4098 First Aid Kit 4380 First Aid Kit 4318 First Aid Kit Vitacilina Premier Value Triple Antibiotic Plus 0.9g Triple Antibiotic 4105 First Aid Kit Aftate Triple Antibiotic Triple Antibiotic plus Pain Relief Maximum Strength Basic Care First Aid Antibiotic and Burn Relief 4111 First Aid Kit 4203 First Aid Kit 4276 First Aid Kit First Aid Triple Antibiotic with Pain Reliever American Safety and First Aid Triple Antibiotic Equate Antibiotic Plus Pain, Itch, Scar Relief meijer Antibiotic Plus Pain Relief Neomycin and Polymyxin B Sulfates, and Bacitracin Zinc 4086 First Aid Kit 4216 First Aid Kit Goodnow Triple Antibiotic UEC Medical First Aid Antibiotic 4204 First Aid Kit Single 0.9g Triple Antibiotic 4265 First Aid Kit Ever Ready First Aid Triple Antibiotic Pomada De La Campana Triple Antibiotic Pain Relief Pomada de Sulfa 4278 First Aid Kit 4333 First Aid Kit 4398 First Aid Kit Johnson and Johnson Safe Travels First Aid Kit Antibiotic K-Mart SmartSense First Aid Contains 303 Pieces PS-2261 Triple Antibiotic, 0.5g Neo-Synalar Genuine First Aid - Home First Aid 4135 First Aid Kit 4172 First Aid Kit Galentic Triple Antibiotic Plus Pain Relief Triple Antibiotic with Pain Relief Maximum Strength 4202 First Aid Kit 4299 First Aid Kit 4329 First Aid Kit Family Wellness Antiseptic and Pain Relief 4052 First Aid Kit Cortisporin GFA First Aid Kit Essentials - 33 Pieces Neosporin Pain Itch Scar 4103 First Aid Kit GENUINE FIRST AID Emergency Preparedness Contains 167 Pieces 4365 First Aid Kit First Aid Triple Antibiotic and Pain Relief Maximum Strength Tripleantibioticapainscaritch 4277 First Aid Kit Crane Safety Triple Antibiotic Odan-spor-HC First Aid Antibiotic Plus Pain Relief Maximum Strength 4076 First Aid Kit ACME FIRST AID Contains 404 PIECES Neomycin and Polymyxin B Sulfates and Bacitracin Zinc Up and Up Antibiotic Plus Pain Relief Antibiotic and Pain Relief Genuine First Aid First Aid Antibiotic Bacitracin Zinc Care Bus and Classroom Yellow Curetech First Aid Face Values Triple Antibiotic FML-neo Oph Sus Publix antibiotic 4332 First Aid Kit ARC FIRST AID Emergency Preparedness Contains 167 PIECES ARC FIRST AID Contains 1000 PIECES Triple Antibiotic and Pain Relief Maximum Strength 4293 First Aid Kit 4362 First Aid Kit Neosporin Plus Pain Relief 4257 First Aid Kit 4379 First Aid Kit Ever Ready Triple Antibiotic 4118 First Aid Kit Bus and Classroom Yellow First Aid Only Antibiotic Neomycin Sulfate Neomycin, Polymyxin B Sulfates and Hydrocortisone Triple Antibiotic Plus Pain Relief Maximum Strength Pediotic Neomycin Easy Care First Aid CVP Triple Antibiotic 4032 First Aid Kit Mycifradin Sulfate Tablets 0.5 Gm 4069 First Aid Kit Neosporin Plus Pain Relief Neo to Go Npd 4334 First Aid Kit Safeway Antibiotic Plus Pain Relief Triple Antibiotic Plus 4283 First Aid Kit 4372 First Aid Kit Neo-poly-dex 4234 First Aid Kit Neo Polycin Dual Action Cream Single Antibiotic with Neomycin Care One Maximum Strength First Aid Antibiotic Triple Antiobiotic ULTRA SEAL Triple Antibiotic Neomycin and Polymyxin B Sulfates and Gramicidin Odan-spor 4245 First Aid Kit 4107 First Aid Kit Neosporin Plus Pain Relief First Aid Antibiotic/Pain Relieving Family Wellness Welly Bravery Balm 4112 First Aid Kit Afassco Triple Antibiotic 4209 First Aid Kit 4327 First Aid Kit 4022 First Aid Kit 4357 First Aid Kit EPIC First Aid 4267 First Aid Kit 4295 First Aid Kit Budpak Triple Antibiotic Maximum Strength 4374 First Aid Kit TopCare Antibiotic Plus Pain Relief Bi-Mart Triple Antibiotic plus Pain Relief Atopalm First Aid Triple Antibiotic Protection Moisturizing and Pain Relief Easy Care First Aid Kit - Outdoor and Travel Johnson and Johnson First Aid All Purpose 160 CT Proctosone Ont 4280 First Aid Kit 4102 First Aid Kit Neocidin 4132 First Aid Kit
Indication	Oral neomycin sulfate is indicated as an adjunctive therapy in hepatic coma (portal-system encephalopathy) by reducing ammonia-forming bacteria in the intestinal tract. It is strongly recommended that oral neomycin is only used in infections that are proven or strongly suspected to be caused by susceptible bacteria to reduce the risk of the development of drug-resistant bacteria.[L11979] Neomycin, in combination with polymyxin B sulfates and hydrocortisone in otic suspensions, is used in the treatment of superficial bacterial infections of the external auditory canal caused by organisms susceptible to the antibiotics. This otic formulation is also used in the treatment of infections of mastoidectomy and fenestration cavities caused by organisms susceptible to the antibiotics.[L10532] The ophthalmic solution containing neomycin in combination with polymyxin B sulfates and dexamethasone is used to treat steroid-responsive inflammatory ocular conditions for which a corticosteroid is indicated and where bacterial infection or a risk of bacterial infection exists.[L10716]
Categories	Agents that produce neuromuscular block (indirect) Alimentary Tract and Metabolism Aminoglycoside Antibacterials Anti-Bacterial Agents Anti-Infective Agents Antibacterials for Systemic Use Antibiotics for Topical Use Antidiarrheals, Intestinal Antiinflammatory/antiinfective Agents Antiinfectives and Antiseptics for Local Oral Treatment Antiinfectives for Systemic Use Blood and Blood Forming Organs Blood Substitutes and Perfusion Solutions Carbohydrates Dermatologicals Drugs that are Mainly Renally Excreted Drugs that are Mainly Renally Excreted with a Narrow Therapeutic Index Enzyme Inhibitors Glycosides Intestinal Antiinfectives Irrigating Solutions Narrow Therapeutic Index Drugs Nephrotoxic agents Neurotoxic agents Ophthalmological and Otological Preparations Ophthalmologicals Otologicals Ototoxic agents Protein Synthesis Inhibitors Sensory Organs Stomatological Preparations Throat Preparations
ATC-Code	A07AA51 R02AB01 J01GB05 D06AX04 S03AA01 A01AB08 A07AA01 S02AA07 B05CA09 S01AA03
CAS number	1404-04-2

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
30S ribosomal protein S12	MATVNQLVRKPRARKVAKSNVPALEACPQKRGVCTRVYTTTPKKPNSALR...	unknown	inhibitor
16S ribosomal RNA	-	unknown	inhibitor
Extracellular calcium-sensing receptor	MAFYSCCWVLLALTWHTSAYGPDQRAQKKGDIILGGLFPIHFGVAAKDQD...	unknown

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682