AMQ

(S)-ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID

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is present as a standalone ligand in 8 entries

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Chemical Component Summary
Name	(S)-ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID
Synonyms	AMPA
Identifiers	(2S)-2-amino-3-(3-hydroxy-5-methyl-1,2-oxazol-4-yl)propanoic acid
Formula	C₇ H₁₀ N₂ O₄
Molecular Weight	186.165
Type	NON-POLYMER
Isomeric SMILES	Cc1c(c(no1)O)C[C@@H](C(=O)O)N
InChI	InChI=1S/C7H10N2O4/c1-3-4(6(10)9-13-3)2-5(8)7(11)12/h5H,2,8H2,1H3,(H,9,10)(H,11,12)/t5-/m0/s1
InChIKey	UUDAMDVQRQNNHZ-YFKPBYRVSA-N

Chemical Details
Formal Charge	0
Atom Count	23
Chiral Atom Count	1
Bond Count	23
Aromatic Bond Count	5

Drug Info: DrugBank

DrugBank ID	DB02057
Name	(S)-AMPA
Groups	experimental
Description	AMPA is a specific agonist for the AMPA receptor.
Synonyms	S-AMPA L-AMPA (S)-AMPA (S)-alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid
CAS number	83643-88-3

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
Glutamate receptor 2	MQKIMHISVLLSPVLWGLIFGVSSNSIQIGGLFPRGADQEYSAFRVGMVQ...	unknown

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682