7KC

PF-3758309


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Chemical Component Summary

NamePF-3758309
Identifiers~{N}-[(1~{S})-2-(dimethylamino)-1-phenyl-ethyl]-6,6-dimethyl-3-[(2-methylthieno[3,2-d]pyrimidin-4-yl)amino]-1,4-dihydropyrrolo[3,4-c]pyrazole-5-carboxamide
FormulaC25 H30 N8 O S
Molecular Weight490.624
TypeNON-POLYMER
Isomeric SMILESCc1nc2ccsc2c(n1)Nc3c4c([nH]n3)C(N(C4)C(=O)N[C@H](CN(C)C)c5ccccc5)(C)C
InChIInChI=1S/C25H30N8OS/c1-15-26-18-11-12-35-20(18)23(27-15)29-22-17-13-33(25(2,3)21(17)30-31-22)24(34)28-19(14-32(4)5)16-9-7-6-8-10-16/h6-12,19H,13-14H2,1-5H3,(H,28,34)(H2,26,27,29,30,31)/t19-/m1/s1
InChIKeyAYCPARAPKDAOEN-LJQANCHMSA-N

Chemical Details

Formal Charge0
Atom Count65
Chiral Atom Count1
Bond Count69
Aromatic Bond Count21

Drug Info: DrugBank

DrugBank IDDB11775 
NamePF-03758309
Groups investigational
DescriptionPF-03758309 has been used in trials studying the treatment of Advanced Solid Tumors.
Synonyms
  • PF-03758309
  • Pf 03758309 Hydrochloride
Categoriesp21-Activated Kinases, antagonists & inhibitors
CAS number898044-15-0

Related Resource References

Resource NameReference
Pharos CHEMBL3128043
PubChem 25227462
ChEMBL CHEMBL3128043
ChEBI CHEBI:93751