706

N-(3,3-dimethyl-2,3-dihydro-1H-indol-6-yl)-2-[(pyridin-4-ylmethyl)amino]pyridine-3-carboxamide


Toggle HydrogenToggle Labels

Chemical Component Summary

NameN-(3,3-dimethyl-2,3-dihydro-1H-indol-6-yl)-2-[(pyridin-4-ylmethyl)amino]pyridine-3-carboxamide
IdentifiersN-(3,3-dimethyl-1,2-dihydroindol-6-yl)-2-(pyridin-4-ylmethylamino)pyridine-3-carboxamide
FormulaC22 H23 N5 O
Molecular Weight373.451
TypeNON-POLYMER
Isomeric SMILESCC1(CNc2c1ccc(c2)NC(=O)c3cccnc3NCc4ccncc4)C
InChIInChI=1S/C22H23N5O/c1-22(2)14-26-19-12-16(5-6-18(19)22)27-21(28)17-4-3-9-24-20(17)25-13-15-7-10-23-11-8-15/h3-12,26H,13-14H2,1-2H3,(H,24,25)(H,27,28)
InChIKeyRAHBGWKEPAQNFF-UHFFFAOYSA-N

Chemical Details

Formal Charge0
Atom Count51
Chiral Atom Count0
Bond Count54
Aromatic Bond Count18

Drug Info: DrugBank

DrugBank IDDB05575 
NameMotesanib
Groups investigational
Synonyms
  • Motesanib phosphate
  • Motesanib diphosphate
  • Motesanib
IndicationInvestigated for use/treatment in solid tumors.
Categories
  • Enzyme Inhibitors
  • Heterocyclic Compounds, Fused-Ring
  • Nicotinic Acids
  • Protein Kinase Inhibitors
  • Pyridines
CAS number453562-69-1

Related Resource References

Resource NameReference
Pharos CHEMBL572881
PubChem 11667893
ChEMBL CHEMBL572881
ChEBI CHEBI:51098