5T1
6-[(1~{R})-1-[8-fluoranyl-6-(1-methylpyrazol-4-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-3-(2-methoxyethoxy)-1,6-naphthyridin-5-one
Find entries where: 5T1
is present as a standalone ligand in 1 entries
Chemical Component Summary | |
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Name | 6-[(1~{R})-1-[8-fluoranyl-6-(1-methylpyrazol-4-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-3-(2-methoxyethoxy)-1,6-naphthyridin-5-one |
Identifiers | 6-[(1~{R})-1-[8-fluoranyl-6-(1-methylpyrazol-4-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-3-(2-methoxyethoxy)-1,6-naphthyridin-5-one |
Formula | C23 H22 F N7 O3 |
Molecular Weight | 463.464 |
Type | NON-POLYMER |
Isomeric SMILES | C[C@H](c1nnc2n1cc(cc2F)c3cnn(c3)C)N4C=Cc5c(cc(cn5)OCCOC)C4=O |
InChI | InChI=1S/C23H22FN7O3/c1-14(30-5-4-20-18(23(30)32)9-17(11-25-20)34-7-6-33-3)21-27-28-22-19(24)8-15(13-31(21)22)16-10-26-29(2)12-16/h4-5,8-14H,6-7H2,1-3H3/t14-/m1/s1 |
InChIKey | DWHXUGDWKAIASB-CQSZACIVSA-N |
Chemical Details | |
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Formal Charge | 0 |
Atom Count | 56 |
Chiral Atom Count | 1 |
Bond Count | 60 |
Aromatic Bond Count | 21 |
Drug Info: DrugBank
DrugBank ID | DB15639 |
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Name | AMG-337 |
Groups | investigational |
Description | AMG-337 is under investigation in clinical trial NCT03147976 (QUILT-3.036: AMG 337 in Subjects With Advanced or Metastatic Solid Tumors). |
Synonyms | AMG-337 |
Categories |
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CAS number | 1173699-31-4 |
Related Resource References
Resource Name | Reference |
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Pharos | CHEMBL3785909 |
PubChem | 44181686 |
ChEMBL | CHEMBL3785909 |