352

(5S)-2-{[(1S)-1-(4-fluorophenyl)ethyl]amino}-5-(1-hydroxy-1-methylethyl)-5-methyl-1,3-thiazol-4(5H)-one

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Chemical Component Summary
Name	(5S)-2-{[(1S)-1-(4-fluorophenyl)ethyl]amino}-5-(1-hydroxy-1-methylethyl)-5-methyl-1,3-thiazol-4(5H)-one
Identifiers	(5S)-2-[[(1S)-1-(4-fluorophenyl)ethyl]amino]-5-(2-hydroxypropan-2-yl)-5-methyl-1,3-thiazol-4-one
Formula	C₁₅ H₁₉ F N₂ O₂ S
Molecular Weight	310.387
Type	NON-POLYMER
Isomeric SMILES	C[C@@H](c1ccc(cc1)F)NC2=NC(=O)[C@](S2)(C)C(C)(C)O
InChI	InChI=1S/C15H19FN2O2S/c1-9(10-5-7-11(16)8-6-10)17-13-18-12(19)15(4,21-13)14(2,3)20/h5-9,20H,1-4H3,(H,17,18,19)/t9-,15+/m0/s1
InChIKey	HYVZYASDRIAOPU-BJOHPYRUSA-N

Chemical Details
Formal Charge	0
Atom Count	40
Chiral Atom Count	2
Bond Count	41
Aromatic Bond Count	6

Drug Info: DrugBank

DrugBank ID	DB07017
Name	(5S)-2-{[(1S)-1-(4-Fluorophenyl)ethyl]amino}-5-(2-hydroxy-2-propanyl)-5-methyl-1,3-thiazol-4(5H)-one
Groups	experimental
Synonyms	(5S)-2-{[(1S)-1-(4-Fluorophenyl)ethyl]amino}-5-(2-hydroxy-2-propanyl)-5-methyl-1,3-thiazol-4(5H)-one

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
Corticosteroid 11-beta-dehydrogenase isozyme 1	MAFMKKYLLPILGLFMAYYYYSANEEFRPEMLQGKKVIVTGASKGIGREM...	unknown

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682