34W

N-{2-[(1S,4R)-6-{[4-(cyclobutylamino)-5-(trifluoromethyl)pyrimidin-2-yl]amino}-1,2,3,4-tetrahydro-1,4-epiminonaphthalen-9-yl]-2-oxoethyl}acetamide


Toggle HydrogenToggle Labels

Chemical Component Summary

NameN-{2-[(1S,4R)-6-{[4-(cyclobutylamino)-5-(trifluoromethyl)pyrimidin-2-yl]amino}-1,2,3,4-tetrahydro-1,4-epiminonaphthalen-9-yl]-2-oxoethyl}acetamide
Identifiersn/a
FormulaC23 H25 F3 N6 O2
Molecular Weight474.479
TypeNON-POLYMER
Isomeric SMILESCC(=O)NCC(=O)N1[C@H]2CC[C@@H]1c3c2ccc(c3)Nc4ncc(c(n4)NC5CCC5)C(F)(F)F
InChIInChI=1S/C23H25F3N6O2/c1-12(33)27-11-20(34)32-18-7-8-19(32)16-9-14(5-6-15(16)18)30-22-28-10-17(23(24,25)26)21(31-22)29-13-3-2-4-13/h5-6,9-10,13,18-19H,2-4,7-8,11H2,1H3,(H,27,33)(H2,28,29,30,31)/t18-,19+/m0/s1
InChIKeyRYYNGWLOYLRZLK-RBUKOAKNSA-N

Chemical Details

Formal Charge0
Atom Count59
Chiral Atom Count2
Bond Count63
Aromatic Bond Count12

Drug Info: DrugBank

DrugBank IDDB13059 
NamePF-03814735
Groups investigational
DescriptionPF-03814735 has been used in trials studying the treatment of Solid Tumors.
SynonymsPF-03814735
Categories
  • Heterocyclic Compounds, Fused-Ring
  • Protein Kinase Inhibitors
CAS number942487-16-3

Related Resource References

Resource NameReference
Pharos CHEMBL4289017
PubChem 51346455
ChEMBL CHEMBL4289017