066

6-{[3-(dimethylcarbamoyl)phenyl]sulfonyl}-4-[(3-methoxyphenyl)amino]-8-methylquinoline-3-carboxamide


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Chemical Component Summary

Name6-{[3-(dimethylcarbamoyl)phenyl]sulfonyl}-4-[(3-methoxyphenyl)amino]-8-methylquinoline-3-carboxamide
Identifiers6-[3-(dimethylcarbamoyl)phenyl]sulfonyl-4-[(3-methoxyphenyl)amino]-8-methyl-quinoline-3-carboxamide
FormulaC27 H26 N4 O5 S
Molecular Weight518.584
TypeNON-POLYMER
Isomeric SMILESCc1cc(cc2c1ncc(c2Nc3cccc(c3)OC)C(=O)N)S(=O)(=O)c4cccc(c4)C(=O)N(C)C
InChIInChI=1S/C27H26N4O5S/c1-16-11-21(37(34,35)20-10-5-7-17(12-20)27(33)31(2)3)14-22-24(16)29-15-23(26(28)32)25(22)30-18-8-6-9-19(13-18)36-4/h5-15H,1-4H3,(H2,28,32)(H,29,30)
InChIKeyJFHROPTYMMSOLG-UHFFFAOYSA-N

Chemical Details

Formal Charge0
Atom Count63
Chiral Atom Count0
Bond Count66
Aromatic Bond Count23

Drug Info: DrugBank

DrugBank IDDB12137 
NameGSK-256066
Groups investigational
DescriptionGsk256066 has been used in trials studying the treatment and diagnostic of SAR, Asthma, Mild Asthma, Allergic Rhinitis, and Seasonal Allergic Rhinitis, among others.
SynonymsGSK-256066
Categories
  • Enzyme Inhibitors
  • Heterocyclic Compounds, Fused-Ring
  • Phosphodiesterase 4 Inhibitors
  • Phosphodiesterase Inhibitors
  • Quinolines
CAS number801312-28-7

Related Resource References

Resource NameReference
PubChem 9827968
ChEMBL CHEMBL570015