8RUU
Fabs derived from bimekizumab in complex with IL-17F
SAbDab Antibody Annotation SAbDab Database Homepage
Chain | Chain Class | Chain Subclass | Chain Type | Antigen Name(s) | Provenance Source |
---|---|---|---|---|---|
A [auth B], D [auth H] | Heavy Chain | IGHV3 | - | interleukin-17f | SAbDab (2024-05-24) |
B [auth C], E [auth L] | Light Chain | IGKV1 | Kappa | interleukin-17f | SAbDab (2024-05-24) |
Thera-SAbDab Antibody Annotation Thera-SAbDab Database Homepage
Chain | Name | Target | Provenance Source |
---|---|---|---|
A [auth B], D [auth H] | Bimekizumab | IL17A, IL17A and IL17F, ALB | Therapeutic SAbDab (2024-05-24) |
B [auth C], E [auth L] | Bimekizumab | IL17A, IL17A and IL17F, ALB | Therapeutic SAbDab (2024-05-24) |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
C [auth X], F [auth Y] | IPR029034 | Cystine-knot cytokine | Homologous Superfamily |
C [auth X], F [auth Y] | IPR010345 | Interleukin-17 family | Family |
C [auth X], F [auth Y] | IPR020440 | Interleukin-17, chordata | Family |