8C5J

Spatial structure of Lch-alpha peptide from two-component lantibiotic system Lichenicidin VK21

External Resource: Annotation

Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification
Protein Modification Annotation

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF14867	Lantibiotic alpha (Lantibiotic_a)	Lantibiotic alpha	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	Lantibiotic lichenicidin VK21 A1	protein binding binding signaling receptor binding	biological process involved in interspecies interaction between organisms response to stimulus response to other organism defense response defense response to Gram-positive bacterium response to external stimulus response to biotic stimulus defense response to bacterium defense response to other organism response to stress response to bacterium response to external biotic stimulus cellular process disruption of cell in another organism biological process involved in interspecies interaction between organisms response to stimulus response to other organism defense response defense response to Gram-positive bacterium response to external stimulus response to biotic stimulus defense response to bacterium defense response to other organism response to stress response to bacterium response to external biotic stimulus cellular process disruption of cell in another organism disruption of anatomical structure in another organism killing of cells of another organism cell killing	extracellular region extracellular space cellular anatomical entity

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR029243	Lantibiotic alpha component	Family

Protein Modification Annotation

Modified Residue(s)
Chain	Residue(s)	Description
A	2KT	RESID: AA0129 PSI-MOD : 2-oxobutanoic acid MOD:00138
A	ABA	Parent Component: ALA RESID: AA0129 , AA0253 , AA0409 PSI-MOD : 2-oxobutanoic acid MOD:00138 , S-(2-aminovinyl)-3-methyl-D-cysteine MOD:00258 , L-2-aminobutanoic acid (Glu) MOD:00819
A	DAL	RESID: AA0129 , AA0253 , AA0409 , AA0111 , AA0191 PSI-MOD : 2-oxobutanoic acid MOD:00138 , S-(2-aminovinyl)-3-methyl-D-cysteine MOD:00258 , L-2-aminobutanoic acid (Glu) MOD:00819 , meso-lanthionine MOD:00120 , D-alanine (Ala) MOD:00198 , D-alanine (Ser) MOD:00858 , D-alanine MOD:00862
A	DBU	Parent Component: THR RESID: AA0129 , AA0253 , AA0409 , AA0111 , AA0191 , AA0182 PSI-MOD : 2-oxobutanoic acid MOD:00138 , S-(2-aminovinyl)-3-methyl-D-cysteine MOD:00258 , L-2-aminobutanoic acid (Glu) MOD:00819 , meso-lanthionine MOD:00120 , D-alanine (Ala) MOD:00198 , D-alanine (Ser) MOD:00858 , D-alanine MOD:00862 , dehydrobutyrine (Thr) MOD:00190 , (Z)-dehydrobutyrine (Thr) MOD:01471
A	DHA	Parent Component: SER RESID: AA0129 , AA0253 , AA0409 , AA0111 , AA0191 , AA0182 , AA0181 PSI-MOD : 2-oxobutanoic acid MOD:00138 , S-(2-aminovinyl)-3-methyl-D-cysteine MOD:00258 , L-2-aminobutanoic acid (Glu) MOD:00819 , meso-lanthionine MOD:00120 , D-alanine (Ala) MOD:00198 , D-alanine (Ser) MOD:00858 , D-alanine MOD:00862 , dehydrobutyrine (Thr) MOD:00190 , (Z)-dehydrobutyrine (Thr) MOD:01471 , dehydroalanine (Ser) MOD:00189 , dehydroalanine (Cys) MOD:00793 , dehydroalanine (Tyr) MOD:00824 , dehydroalanine MOD:01168 , dehydroalanine (Sec) MOD:01954

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.