Annotations: 7LVB

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A [auth D]	SCOP2B Superfamily	Bacterial enterotoxins	8080121	3000434	SCOP2B (2022-06-29)
B [auth E]	SCOP2B Superfamily	Bacterial enterotoxins	8080121	3000434	SCOP2B (2022-06-29)
C [auth F]	SCOP2B Superfamily	Bacterial enterotoxins	8080121	3000434	SCOP2B (2022-06-29)
D [auth G]	SCOP2B Superfamily	Bacterial enterotoxins	8080121	3000434	SCOP2B (2022-06-29)
E [auth H]	SCOP2B Superfamily	Bacterial enterotoxins	8080121	3000434	SCOP2B (2022-06-29)
F [auth A]	SCOP2B Superfamily	Bacterial enterotoxins	8080121	3000434	SCOP2B (2022-06-29)
G [auth B]	SCOP2B Superfamily	Bacterial enterotoxins	8080121	3000434	SCOP2B (2022-06-29)
H [auth C]	SCOP2B Superfamily	Bacterial enterotoxins	8080121	3000434	SCOP2B (2022-06-29)
I	SCOP2B Superfamily	Bacterial enterotoxins	8080121	3000434	SCOP2B (2022-06-29)
J	SCOP2B Superfamily	Bacterial enterotoxins	8080121	3000434	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A [auth D]	PF01376	e7lvbD1	A: beta barrels	X: OB-fold	H: Bacterial enterotoxins (From Topology)	T: Bacterial enterotoxins	F: PF01376	ECOD (1.6)
B [auth E]	PF01376	e7lvbE1	A: beta barrels	X: OB-fold	H: Bacterial enterotoxins (From Topology)	T: Bacterial enterotoxins	F: PF01376	ECOD (1.6)
C [auth F]	PF01376	e7lvbF1	A: beta barrels	X: OB-fold	H: Bacterial enterotoxins (From Topology)	T: Bacterial enterotoxins	F: PF01376	ECOD (1.6)
D [auth G]	PF01376	e7lvbG1	A: beta barrels	X: OB-fold	H: Bacterial enterotoxins (From Topology)	T: Bacterial enterotoxins	F: PF01376	ECOD (1.6)
E [auth H]	PF01376	e7lvbH1	A: beta barrels	X: OB-fold	H: Bacterial enterotoxins (From Topology)	T: Bacterial enterotoxins	F: PF01376	ECOD (1.6)
F [auth A]	PF01376	e7lvbA1	A: beta barrels	X: OB-fold	H: Bacterial enterotoxins (From Topology)	T: Bacterial enterotoxins	F: PF01376	ECOD (1.6)
G [auth B]	PF01376	e7lvbB1	A: beta barrels	X: OB-fold	H: Bacterial enterotoxins (From Topology)	T: Bacterial enterotoxins	F: PF01376	ECOD (1.6)
H [auth C]	PF01376	e7lvbC1	A: beta barrels	X: OB-fold	H: Bacterial enterotoxins (From Topology)	T: Bacterial enterotoxins	F: PF01376	ECOD (1.6)
I	PF01376	e7lvbI1	A: beta barrels	X: OB-fold	H: Bacterial enterotoxins (From Topology)	T: Bacterial enterotoxins	F: PF01376	ECOD (1.6)
J	PF01376	e7lvbJ1	A: beta barrels	X: OB-fold	H: Bacterial enterotoxins (From Topology)	T: Bacterial enterotoxins	F: PF01376	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A [auth D], B [auth E], C [auth F], D [auth G], E [auth H], A [auth D], B [auth E], C [auth F], D [auth G], E [auth H], F [auth A], G [auth B], H [auth C], I, J	PF00516	Envelope glycoprotein GP120 (GP120)	Envelope glycoprotein GP120	-	Family
A [auth D], B [auth E], C [auth F], D [auth G], E [auth H], A [auth D], B [auth E], C [auth F], D [auth G], E [auth H], F [auth A], G [auth B], H [auth C], I, J	PF01376	Heat-labile enterotoxin beta chain (Enterotoxin_b)	Heat-labile enterotoxin beta chain	-	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A [auth D], B [auth E], C [auth F], D [auth G], E [auth H], A [auth D], B [auth E], C [auth F], D [auth G], E [auth H], F [auth A], G [auth B], H [auth C], I, J	Cholera enterotoxin B-subunit,Surface protein gp120	structural molecule activity binding galactose binding monosaccharide binding carbohydrate binding small molecule binding host cell surface binding toxin activity	viral process membrane fusion involved in viral entry into host cell biological process involved in interspecies interaction between organisms symbiont entry into host cell symbiont entry into host viral life cycle biological process involved in interaction with host biological process involved in symbiotic interaction virion attachment to host cell adhesion of symbiont to host cell adhesion of symbiont to host cellular response to stimulus regulation of cellular process response to stimulus viral process membrane fusion involved in viral entry into host cell biological process involved in interspecies interaction between organisms symbiont entry into host cell symbiont entry into host viral life cycle biological process involved in interaction with host biological process involved in symbiotic interaction virion attachment to host cell adhesion of symbiont to host cell adhesion of symbiont to host cellular response to stimulus regulation of cellular process response to stimulus positive regulation of phosphorylation positive regulation of phosphate metabolic process cell communication regulation of primary metabolic process positive regulation of metabolic process regulation of phosphate metabolic process peptidyl-amino acid modification phosphate-containing compound metabolic process positive regulation of macromolecule metabolic process signal transduction protein modification process phosphorus metabolic process positive regulation of protein phosphorylation tyrosine phosphorylation of STAT protein regulation of biological process protein phosphorylation positive regulation of phosphorus metabolic process phosphorylation cellular metabolic process regulation of protein metabolic process primary metabolic process regulation of cellular metabolic process macromolecule modification metabolic process regulation of phosphorus metabolic process macromolecule metabolic process regulation of metabolic process cell surface receptor signaling pathway via STAT regulation of protein modification process signaling regulation of protein phosphorylation positive regulation of protein metabolic process positive regulation of biological process positive regulation of cellular metabolic process peptidyl-tyrosine modification positive regulation of peptidyl-tyrosine phosphorylation positive regulation of protein modification process organic substance metabolic process protein metabolic process positive regulation of cellular process organonitrogen compound metabolic process cell surface receptor signaling pathway regulation of tyrosine phosphorylation of STAT protein biological regulation regulation of peptidyl-tyrosine phosphorylation regulation of macromolecule metabolic process positive regulation of tyrosine phosphorylation of STAT protein cellular process regulation of phosphorylation peptidyl-tyrosine phosphorylation cell surface receptor signaling pathway via JAK-STAT	virion component viral membrane viral envelope membrane cellular anatomical entity host cell plasma membrane host cellular component host cell part host cell membrane virion membrane host intracellular membrane-bounded organelle host intracellular part host cell cytoplasm part host intracellular organelle virion component viral membrane viral envelope membrane cellular anatomical entity host cell plasma membrane host cellular component host cell part host cell membrane virion membrane host intracellular membrane-bounded organelle host intracellular part host cell cytoplasm part host intracellular organelle host cell endosome membrane host cell cytoplasm host cell endosome host intracellular region periplasmic space protein-containing complex catalytic complex extracellular region

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A [auth D], B [auth E], C [auth F], D [auth G], E [auth H], A [auth D], B [auth E], C [auth F], D [auth G], E [auth H], F [auth A], G [auth B], H [auth C], I, J	IPR000777	Human immunodeficiency virus 1, envelope glycoprotein Gp120	Domain
A [auth D], B [auth E], C [auth F], D [auth G], E [auth H], A [auth D], B [auth E], C [auth F], D [auth G], E [auth H], F [auth A], G [auth B], H [auth C], I, J	IPR036377	Gp120 core superfamily	Homologous Superfamily
A [auth D], B [auth E], C [auth F], D [auth G], E [auth H], A [auth D], B [auth E], C [auth F], D [auth G], E [auth H], F [auth A], G [auth B], H [auth C], I, J	IPR000328	Retroviral envelope protein GP41-like	Domain
A [auth D], B [auth E], C [auth F], D [auth G], E [auth H], A [auth D], B [auth E], C [auth F], D [auth G], E [auth H], F [auth A], G [auth B], H [auth C], I, J	IPR001835	Heat-labile enterotoxin, B chain	Family
A [auth D], B [auth E], C [auth F], D [auth G], E [auth H], A [auth D], B [auth E], C [auth F], D [auth G], E [auth H], F [auth A], G [auth B], H [auth C], I, J	IPR008992	Enterotoxin	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.