7AQO
yeast THO-Sub2 complex dimer
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
C [auth K] | PF00400 | e7aqoK1 | A: beta duplicates or obligate multimers | X: beta-propeller-like | H: beta-propeller | T: 7-bladed | F: PF00400 | ECOD (1.6) |
G [auth E] | PF00400 | e7aqoE1 | A: beta duplicates or obligate multimers | X: beta-propeller-like | H: beta-propeller | T: 7-bladed | F: PF00400 | ECOD (1.6) |
D [auth L] | PF00270 | e7aqoL2 | A: a/b three-layered sandwiches | X: P-loop domains-like | H: P-loop domains-related | T: P-loop containing nucleoside triphosphate hydrolases | F: PF00270 | ECOD (1.6) |
D [auth L] | PF00271 | e7aqoL1 | A: a/b three-layered sandwiches | X: P-loop domains-like | H: P-loop domains-related | T: P-loop containing nucleoside triphosphate hydrolases | F: PF00271 | ECOD (1.6) |
H [auth F] | PF00270 | e7aqoF2 | A: a/b three-layered sandwiches | X: P-loop domains-like | H: P-loop domains-related | T: P-loop containing nucleoside triphosphate hydrolases | F: PF00270 | ECOD (1.6) |
H [auth F] | PF00271 | e7aqoF1 | A: a/b three-layered sandwiches | X: P-loop domains-like | H: P-loop domains-related | T: P-loop containing nucleoside triphosphate hydrolases | F: PF00271 | ECOD (1.6) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
A [auth G], E [auth A] | PF16134 | THO complex subunit 2 N-terminus (THOC2_N) | THO complex subunit 2 N-terminus | - | Family |
A [auth G], E [auth A] | PF11262 | Transcription factor/nuclear export subunit protein 2 (Tho2) | Transcription factor/nuclear export subunit protein 2 | - | Family |
A [auth G], E [auth A] | PF11732 | Transcription- and export-related complex subunit (Thoc2) | Transcription- and export-related complex subunit | - | Family |
B [auth H], F [auth B] | PF11957 | THO complex subunit 1 transcription elongation factor (efThoc1) | THO complex subunit 1 transcription elongation factor | - | Family |
C [auth K], G [auth E] | PF00400 | WD domain, G-beta repeat (WD40) | WD domain, G-beta repeat | - | Repeat |
D [auth L], H [auth F] | PF00271 | Helicase conserved C-terminal domain (Helicase_C) | Helicase conserved C-terminal domain | The Prosite family is restricted to DEAD/H helicases, whereas this domain family is found in a wide variety of helicases and helicase related proteins. It may be that this is not an autonomously folding unit, but an integral part of the helicase. | Domain |
I [auth J], K [auth C] | PF09432 | Tho complex subunit THP2 (THP2) | Tho complex subunit THP2 | - | Family |
J [auth I], L [auth D] | PF05615 | Tho complex subunit 7 (THOC7) | Tho complex subunit 7 | - | Family |