Annotations: 6V0F

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF02470	e6v0fA1	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: Mammalian cell entry (MCE) domain	F: PF02470	ECOD (1.6)
B	PF02470	e6v0fB1	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: Mammalian cell entry (MCE) domain	F: PF02470	ECOD (1.6)
C	PF02470	e6v0fC1	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: Mammalian cell entry (MCE) domain	F: PF02470	ECOD (1.6)
D	PF02470	e6v0fD1	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: Mammalian cell entry (MCE) domain	F: PF02470	ECOD (1.6)
E	PF02470	e6v0fE1	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: Mammalian cell entry (MCE) domain	F: PF02470	ECOD (1.6)
F	PF02470	e6v0fF1	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: Mammalian cell entry (MCE) domain	F: PF02470	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D, E A, B, C, D, E, F	PF02470	MlaD protein (MlaD)	MlaD protein	This family of proteins contains MlaD, which is a component of the Mla pathway, an ABC transport system that functions to maintain the asymmetry of the outer membrane [1]. The family also contains the mce (mammalian cell entry) proteins from Mycobact ...	This family of proteins contains MlaD, which is a component of the Mla pathway, an ABC transport system that functions to maintain the asymmetry of the outer membrane [1]. The family also contains the mce (mammalian cell entry) proteins from Mycobacterium tuberculosis. The archetype (Rv0169), was isolated as being necessary for colonisation of, and survival within, the macrophage [2]. This family contains proteins of unknown function from other bacteria.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E A, B, C, D, E, F	Intermembrane transport protein YebT	identical protein binding protein binding binding	membrane organization intermembrane lipid transfer transport organic substance transport lipid localization lipid transport establishment of localization cellular component organization localization macromolecule localization cellular process cellular component organization or biogenesis	cell periphery plasma membrane membrane cellular anatomical entity outer membrane-bounded periplasmic space cell envelope periplasmic space

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E A, B, C, D, E, F	IPR003399	Mce/MlaD	Domain

Membrane Protein Annotation: OPM OPM Database Homepage

Chains	External Link	Type	Class	Superfamily	Family
A, B, C, D, E A, B, C, D, E, F	OPM	Transmembrane	Alpha-helical polytopic	ABC transporters	MlaD/MlaE transporter

Membrane Protein Annotation: mpstruc mpstruc Database Homepage

Chains	Resource Link	Group	Subgroup	Protein
A, B, C, D, E A, B, C, D, E, F	mpstruc	TRANSMEMBRANE PROTEINS: BETA-BARREL	Beta-Barrel Membrane Proteins: Monomeric/Dimeric	LetB lipophilic Envelope-spanning Tunnel B, model 1

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.