6S5U

Strictosidine Synthase from Ophiorrhiza pumila in complex with N-[2-(1H-Indol-3-yl)ethyl]-3-methyl-1-butanamine

External Resource: Annotation

Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF03088	e6s5uA1	A: beta duplicates or obligate multimers	X: beta-propeller-like	H: beta-propeller	T: 6-bladed	F: PF03088	ECOD (1.6)
B [auth C]	PF03088	e6s5uC1	A: beta duplicates or obligate multimers	X: beta-propeller-like	H: beta-propeller	T: 6-bladed	F: PF03088	ECOD (1.6)
C [auth B]	PF03088	e6s5uB1	A: beta duplicates or obligate multimers	X: beta-propeller-like	H: beta-propeller	T: 6-bladed	F: PF03088	ECOD (1.6)
D	PF03088	e6s5uD1	A: beta duplicates or obligate multimers	X: beta-propeller-like	H: beta-propeller	T: 6-bladed	F: PF03088	ECOD (1.6)
E	PF03088	e6s5uE1	A: beta duplicates or obligate multimers	X: beta-propeller-like	H: beta-propeller	T: 6-bladed	F: PF03088	ECOD (1.6)
F	PF03088	e6s5uF1	A: beta duplicates or obligate multimers	X: beta-propeller-like	H: beta-propeller	T: 6-bladed	F: PF03088	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	2.120.10.30	Mainly Beta	6 Propeller	Neuraminidase	TolB, C-terminal domain	CATH (utative)
B [auth C]	2.120.10.30	Mainly Beta	6 Propeller	Neuraminidase	TolB, C-terminal domain	CATH (utative)
C [auth B]	2.120.10.30	Mainly Beta	6 Propeller	Neuraminidase	TolB, C-terminal domain	CATH (utative)
D	2.120.10.30	Mainly Beta	6 Propeller	Neuraminidase	TolB, C-terminal domain	CATH (utative)
E	2.120.10.30	Mainly Beta	6 Propeller	Neuraminidase	TolB, C-terminal domain	CATH (utative)
F	2.120.10.30	Mainly Beta	6 Propeller	Neuraminidase	TolB, C-terminal domain	CATH (utative)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B [auth C], C [auth B], D, E, A, B [auth C], C [auth B], D, E, F	PF20067	Strictosidine synthase-like, N-terminal (SSL_N)	Strictosidine synthase-like, N-terminal	-	Repeat
A, B [auth C], C [auth B], D, E, A, B [auth C], C [auth B], D, E, F	PF03088	Strictosidine synthase (Str_synth)	Strictosidine synthase	-	Repeat

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B [auth C], C [auth B], D, E, A, B [auth C], C [auth B], D, E, F	Strictosidine synthase	hydrolase activity catalytic activity amine-lyase activity lyase activity strictosidine synthase activity carbon-nitrogen lyase activity	biosynthetic process metabolic process	cellular anatomical entity endomembrane system membrane-bounded organelle intracellular organelle intracellular anatomical structure organelle vacuole cytoplasm intracellular membrane-bounded organelle

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B [auth C], C [auth B], D, E, A, B [auth C], C [auth B], D, E, F	IPR011042	Six-bladed beta-propeller, TolB-like	Homologous Superfamily
A, B [auth C], C [auth B], D, E, A, B [auth C], C [auth B], D, E, F	IPR018119	Strictosidine synthase, conserved region	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.