Annotations: 6S4C

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF00092	e6s4cA1	A: a/b three-layered sandwiches	X: HAD domain-like	H: HAD domain-related	T: vWA-like	F: PF00092	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF00092	von Willebrand factor type A domain (VWA)	von Willebrand factor type A domain	-	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	Collagen alpha-1(VII) chain	structural molecule activity extracellular matrix structural constituent extracellular matrix structural constituent conferring tensile strength enzyme regulator activity molecular function inhibitor activity peptidase regulator activity serine-type endopeptidase inhibitor activity molecular function regulator activity enzyme inhibitor activity peptidase inhibitor activity endopeptidase regulator activity endopeptidase inhibitor activity identical protein binding protein binding structural molecule activity extracellular matrix structural constituent extracellular matrix structural constituent conferring tensile strength enzyme regulator activity molecular function inhibitor activity peptidase regulator activity serine-type endopeptidase inhibitor activity molecular function regulator activity enzyme inhibitor activity peptidase inhibitor activity endopeptidase regulator activity endopeptidase inhibitor activity identical protein binding protein binding binding	cell adhesion cellular process cellular component organization extracellular matrix organization cellular component organization or biogenesis extracellular structure organization external encapsulating structure organization	protein-containing complex collagen trimer extracellular region cellular anatomical entity basement membrane cell periphery extracellular matrix external encapsulating structure collagen-containing extracellular matrix extracellular space

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR008160	Collagen triple helix repeat	Repeat
A	IPR003961	Fibronectin type III	Domain
A	IPR036465	von Willebrand factor A-like domain superfamily	Homologous Superfamily
A	IPR020901	Proteinase inhibitor I2, Kunitz, conserved site	Conserved Site
A	IPR036880	Pancreatic trypsin inhibitor Kunitz domain superfamily	Homologous Superfamily
A	IPR002223	Pancreatic trypsin inhibitor Kunitz domain	Domain
A	IPR013783	Immunoglobulin-like fold	Homologous Superfamily
A	IPR002035	von Willebrand factor, type A	Domain
A	IPR036116	Fibronectin type III superfamily	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.