Annotations: 6RME

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, G	PF06437	IMP-specific 5'-nucleotidase (ISN1)	IMP-specific 5'-nucleotidase	-	Family
B, D	PF06437	IMP-specific 5'-nucleotidase (ISN1)	IMP-specific 5'-nucleotidase	-	Family
C	PF06437	IMP-specific 5'-nucleotidase (ISN1)	IMP-specific 5'-nucleotidase	-	Family
E, H	PF06437	IMP-specific 5'-nucleotidase (ISN1)	IMP-specific 5'-nucleotidase	-	Family
F	PF06437	IMP-specific 5'-nucleotidase (ISN1)	IMP-specific 5'-nucleotidase	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, G	IMP-specific 5'-nucleotidase, putative	cation binding magnesium ion binding ion binding binding metal ion binding small molecule binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding purine nucleotide binding organic cyclic compound binding anion binding cation binding magnesium ion binding ion binding binding metal ion binding small molecule binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding phosphoric ester hydrolase activity nucleotidase activity hydrolase activity, acting on ester bonds phosphatase activity hydrolase activity IMP 5'-nucleotidase activity 5'-nucleotidase activity catalytic activity	glycosyl compound metabolic process organonitrogen compound biosynthetic process carbohydrate derivative metabolic process nucleoside biosynthetic process nucleobase-containing compound metabolic process organic substance metabolic process nucleobase-containing small molecule metabolic process purine-containing compound biosynthetic process organic substance biosynthetic process small molecule metabolic process cellular metabolic compound salvage purine ribonucleoside metabolic process carbohydrate derivative biosynthetic process organonitrogen compound metabolic process glycosyl compound metabolic process organonitrogen compound biosynthetic process carbohydrate derivative metabolic process nucleoside biosynthetic process nucleobase-containing compound metabolic process organic substance metabolic process nucleobase-containing small molecule metabolic process purine-containing compound biosynthetic process organic substance biosynthetic process small molecule metabolic process cellular metabolic compound salvage purine ribonucleoside metabolic process carbohydrate derivative biosynthetic process organonitrogen compound metabolic process glycosyl compound biosynthetic process purine-containing compound salvage inosine metabolic process small molecule biosynthetic process nucleoside salvage cellular metabolic process inosine salvage purine ribonucleoside biosynthetic process primary metabolic process ribonucleoside biosynthetic process nucleobase-containing compound biosynthetic process nucleoside metabolic process nucleobase-containing small molecule biosynthetic process purine-containing compound metabolic process inosine biosynthetic process organic cyclic compound metabolic process purine ribonucleoside salvage biosynthetic process purine nucleoside biosynthetic process organic cyclic compound biosynthetic process metabolic process cellular process purine nucleoside metabolic process ribonucleoside metabolic process IMP metabolic process ribose phosphate metabolic process ribonucleotide catabolic process catabolic process organophosphate catabolic process nucleoside phosphate catabolic process purine ribonucleoside monophosphate catabolic process purine nucleoside monophosphate catabolic process purine ribonucleoside monophosphate metabolic process purine nucleotide metabolic process ribonucleotide metabolic process ribonucleoside monophosphate metabolic process purine nucleoside monophosphate metabolic process phosphate-containing compound metabolic process ribonucleoside monophosphate catabolic process purine ribonucleotide catabolic process phosphorus metabolic process nucleoside monophosphate metabolic process nucleotide catabolic process nucleoside phosphate metabolic process organonitrogen compound catabolic process purine nucleotide catabolic process carbohydrate derivative catabolic process nucleoside monophosphate catabolic process purine-containing compound catabolic process nucleotide metabolic process organic cyclic compound catabolic process IMP catabolic process nucleobase-containing compound catabolic process organophosphate metabolic process purine ribonucleotide metabolic process organic substance catabolic process pyridine nucleoside biosynthetic process pyridine-containing compound metabolic process nicotinamide riboside biosynthetic process nicotinamide riboside metabolic process pyridine-containing compound biosynthetic process pyridine nucleoside metabolic process nicotinic acid riboside metabolic process nicotinic acid riboside biosynthetic process	intracellular anatomical structure cytoplasm cellular anatomical entity
B, D	IMP-specific 5'-nucleotidase, putative	cation binding magnesium ion binding ion binding binding metal ion binding small molecule binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding purine nucleotide binding organic cyclic compound binding anion binding cation binding magnesium ion binding ion binding binding metal ion binding small molecule binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding phosphoric ester hydrolase activity nucleotidase activity hydrolase activity, acting on ester bonds phosphatase activity hydrolase activity IMP 5'-nucleotidase activity 5'-nucleotidase activity catalytic activity	glycosyl compound metabolic process organonitrogen compound biosynthetic process carbohydrate derivative metabolic process nucleoside biosynthetic process nucleobase-containing compound metabolic process organic substance metabolic process nucleobase-containing small molecule metabolic process purine-containing compound biosynthetic process organic substance biosynthetic process small molecule metabolic process cellular metabolic compound salvage purine ribonucleoside metabolic process carbohydrate derivative biosynthetic process organonitrogen compound metabolic process glycosyl compound metabolic process organonitrogen compound biosynthetic process carbohydrate derivative metabolic process nucleoside biosynthetic process nucleobase-containing compound metabolic process organic substance metabolic process nucleobase-containing small molecule metabolic process purine-containing compound biosynthetic process organic substance biosynthetic process small molecule metabolic process cellular metabolic compound salvage purine ribonucleoside metabolic process carbohydrate derivative biosynthetic process organonitrogen compound metabolic process glycosyl compound biosynthetic process purine-containing compound salvage inosine metabolic process small molecule biosynthetic process nucleoside salvage cellular metabolic process inosine salvage purine ribonucleoside biosynthetic process primary metabolic process ribonucleoside biosynthetic process nucleobase-containing compound biosynthetic process nucleoside metabolic process nucleobase-containing small molecule biosynthetic process purine-containing compound metabolic process inosine biosynthetic process organic cyclic compound metabolic process purine ribonucleoside salvage biosynthetic process purine nucleoside biosynthetic process organic cyclic compound biosynthetic process metabolic process cellular process purine nucleoside metabolic process ribonucleoside metabolic process IMP metabolic process ribose phosphate metabolic process ribonucleotide catabolic process catabolic process organophosphate catabolic process nucleoside phosphate catabolic process purine ribonucleoside monophosphate catabolic process purine nucleoside monophosphate catabolic process purine ribonucleoside monophosphate metabolic process purine nucleotide metabolic process ribonucleotide metabolic process ribonucleoside monophosphate metabolic process purine nucleoside monophosphate metabolic process phosphate-containing compound metabolic process ribonucleoside monophosphate catabolic process purine ribonucleotide catabolic process phosphorus metabolic process nucleoside monophosphate metabolic process nucleotide catabolic process nucleoside phosphate metabolic process organonitrogen compound catabolic process purine nucleotide catabolic process carbohydrate derivative catabolic process nucleoside monophosphate catabolic process purine-containing compound catabolic process nucleotide metabolic process organic cyclic compound catabolic process IMP catabolic process nucleobase-containing compound catabolic process organophosphate metabolic process purine ribonucleotide metabolic process organic substance catabolic process pyridine nucleoside biosynthetic process pyridine-containing compound metabolic process nicotinamide riboside biosynthetic process nicotinamide riboside metabolic process pyridine-containing compound biosynthetic process pyridine nucleoside metabolic process nicotinic acid riboside metabolic process nicotinic acid riboside biosynthetic process	intracellular anatomical structure cytoplasm cellular anatomical entity
C	IMP-specific 5'-nucleotidase, putative	cation binding magnesium ion binding ion binding binding metal ion binding small molecule binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding purine nucleotide binding organic cyclic compound binding anion binding cation binding magnesium ion binding ion binding binding metal ion binding small molecule binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding phosphoric ester hydrolase activity nucleotidase activity hydrolase activity, acting on ester bonds phosphatase activity hydrolase activity IMP 5'-nucleotidase activity 5'-nucleotidase activity catalytic activity	glycosyl compound metabolic process organonitrogen compound biosynthetic process carbohydrate derivative metabolic process nucleoside biosynthetic process nucleobase-containing compound metabolic process organic substance metabolic process nucleobase-containing small molecule metabolic process purine-containing compound biosynthetic process organic substance biosynthetic process small molecule metabolic process cellular metabolic compound salvage purine ribonucleoside metabolic process carbohydrate derivative biosynthetic process organonitrogen compound metabolic process glycosyl compound metabolic process organonitrogen compound biosynthetic process carbohydrate derivative metabolic process nucleoside biosynthetic process nucleobase-containing compound metabolic process organic substance metabolic process nucleobase-containing small molecule metabolic process purine-containing compound biosynthetic process organic substance biosynthetic process small molecule metabolic process cellular metabolic compound salvage purine ribonucleoside metabolic process carbohydrate derivative biosynthetic process organonitrogen compound metabolic process glycosyl compound biosynthetic process purine-containing compound salvage inosine metabolic process small molecule biosynthetic process nucleoside salvage cellular metabolic process inosine salvage purine ribonucleoside biosynthetic process primary metabolic process ribonucleoside biosynthetic process nucleobase-containing compound biosynthetic process nucleoside metabolic process nucleobase-containing small molecule biosynthetic process purine-containing compound metabolic process inosine biosynthetic process organic cyclic compound metabolic process purine ribonucleoside salvage biosynthetic process purine nucleoside biosynthetic process organic cyclic compound biosynthetic process metabolic process cellular process purine nucleoside metabolic process ribonucleoside metabolic process IMP metabolic process ribose phosphate metabolic process ribonucleotide catabolic process catabolic process organophosphate catabolic process nucleoside phosphate catabolic process purine ribonucleoside monophosphate catabolic process purine nucleoside monophosphate catabolic process purine ribonucleoside monophosphate metabolic process purine nucleotide metabolic process ribonucleotide metabolic process ribonucleoside monophosphate metabolic process purine nucleoside monophosphate metabolic process phosphate-containing compound metabolic process ribonucleoside monophosphate catabolic process purine ribonucleotide catabolic process phosphorus metabolic process nucleoside monophosphate metabolic process nucleotide catabolic process nucleoside phosphate metabolic process organonitrogen compound catabolic process purine nucleotide catabolic process carbohydrate derivative catabolic process nucleoside monophosphate catabolic process purine-containing compound catabolic process nucleotide metabolic process organic cyclic compound catabolic process IMP catabolic process nucleobase-containing compound catabolic process organophosphate metabolic process purine ribonucleotide metabolic process organic substance catabolic process pyridine nucleoside biosynthetic process pyridine-containing compound metabolic process nicotinamide riboside biosynthetic process nicotinamide riboside metabolic process pyridine-containing compound biosynthetic process pyridine nucleoside metabolic process nicotinic acid riboside metabolic process nicotinic acid riboside biosynthetic process	intracellular anatomical structure cytoplasm cellular anatomical entity
E, H	IMP-specific 5'-nucleotidase, putative	cation binding magnesium ion binding ion binding binding metal ion binding small molecule binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding purine nucleotide binding organic cyclic compound binding anion binding cation binding magnesium ion binding ion binding binding metal ion binding small molecule binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding phosphoric ester hydrolase activity nucleotidase activity hydrolase activity, acting on ester bonds phosphatase activity hydrolase activity IMP 5'-nucleotidase activity 5'-nucleotidase activity catalytic activity	glycosyl compound metabolic process organonitrogen compound biosynthetic process carbohydrate derivative metabolic process nucleoside biosynthetic process nucleobase-containing compound metabolic process organic substance metabolic process nucleobase-containing small molecule metabolic process purine-containing compound biosynthetic process organic substance biosynthetic process small molecule metabolic process cellular metabolic compound salvage purine ribonucleoside metabolic process carbohydrate derivative biosynthetic process organonitrogen compound metabolic process glycosyl compound metabolic process organonitrogen compound biosynthetic process carbohydrate derivative metabolic process nucleoside biosynthetic process nucleobase-containing compound metabolic process organic substance metabolic process nucleobase-containing small molecule metabolic process purine-containing compound biosynthetic process organic substance biosynthetic process small molecule metabolic process cellular metabolic compound salvage purine ribonucleoside metabolic process carbohydrate derivative biosynthetic process organonitrogen compound metabolic process glycosyl compound biosynthetic process purine-containing compound salvage inosine metabolic process small molecule biosynthetic process nucleoside salvage cellular metabolic process inosine salvage purine ribonucleoside biosynthetic process primary metabolic process ribonucleoside biosynthetic process nucleobase-containing compound biosynthetic process nucleoside metabolic process nucleobase-containing small molecule biosynthetic process purine-containing compound metabolic process inosine biosynthetic process organic cyclic compound metabolic process purine ribonucleoside salvage biosynthetic process purine nucleoside biosynthetic process organic cyclic compound biosynthetic process metabolic process cellular process purine nucleoside metabolic process ribonucleoside metabolic process IMP metabolic process ribose phosphate metabolic process ribonucleotide catabolic process catabolic process organophosphate catabolic process nucleoside phosphate catabolic process purine ribonucleoside monophosphate catabolic process purine nucleoside monophosphate catabolic process purine ribonucleoside monophosphate metabolic process purine nucleotide metabolic process ribonucleotide metabolic process ribonucleoside monophosphate metabolic process purine nucleoside monophosphate metabolic process phosphate-containing compound metabolic process ribonucleoside monophosphate catabolic process purine ribonucleotide catabolic process phosphorus metabolic process nucleoside monophosphate metabolic process nucleotide catabolic process nucleoside phosphate metabolic process organonitrogen compound catabolic process purine nucleotide catabolic process carbohydrate derivative catabolic process nucleoside monophosphate catabolic process purine-containing compound catabolic process nucleotide metabolic process organic cyclic compound catabolic process IMP catabolic process nucleobase-containing compound catabolic process organophosphate metabolic process purine ribonucleotide metabolic process organic substance catabolic process pyridine nucleoside biosynthetic process pyridine-containing compound metabolic process nicotinamide riboside biosynthetic process nicotinamide riboside metabolic process pyridine-containing compound biosynthetic process pyridine nucleoside metabolic process nicotinic acid riboside metabolic process nicotinic acid riboside biosynthetic process	intracellular anatomical structure cytoplasm cellular anatomical entity
F	IMP-specific 5'-nucleotidase, putative	cation binding magnesium ion binding ion binding binding metal ion binding small molecule binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding purine nucleotide binding organic cyclic compound binding anion binding cation binding magnesium ion binding ion binding binding metal ion binding small molecule binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding phosphoric ester hydrolase activity nucleotidase activity hydrolase activity, acting on ester bonds phosphatase activity hydrolase activity IMP 5'-nucleotidase activity 5'-nucleotidase activity catalytic activity	glycosyl compound metabolic process organonitrogen compound biosynthetic process carbohydrate derivative metabolic process nucleoside biosynthetic process nucleobase-containing compound metabolic process organic substance metabolic process nucleobase-containing small molecule metabolic process purine-containing compound biosynthetic process organic substance biosynthetic process small molecule metabolic process cellular metabolic compound salvage purine ribonucleoside metabolic process carbohydrate derivative biosynthetic process organonitrogen compound metabolic process glycosyl compound metabolic process organonitrogen compound biosynthetic process carbohydrate derivative metabolic process nucleoside biosynthetic process nucleobase-containing compound metabolic process organic substance metabolic process nucleobase-containing small molecule metabolic process purine-containing compound biosynthetic process organic substance biosynthetic process small molecule metabolic process cellular metabolic compound salvage purine ribonucleoside metabolic process carbohydrate derivative biosynthetic process organonitrogen compound metabolic process glycosyl compound biosynthetic process purine-containing compound salvage inosine metabolic process small molecule biosynthetic process nucleoside salvage cellular metabolic process inosine salvage purine ribonucleoside biosynthetic process primary metabolic process ribonucleoside biosynthetic process nucleobase-containing compound biosynthetic process nucleoside metabolic process nucleobase-containing small molecule biosynthetic process purine-containing compound metabolic process inosine biosynthetic process organic cyclic compound metabolic process purine ribonucleoside salvage biosynthetic process purine nucleoside biosynthetic process organic cyclic compound biosynthetic process metabolic process cellular process purine nucleoside metabolic process ribonucleoside metabolic process IMP metabolic process ribose phosphate metabolic process ribonucleotide catabolic process catabolic process organophosphate catabolic process nucleoside phosphate catabolic process purine ribonucleoside monophosphate catabolic process purine nucleoside monophosphate catabolic process purine ribonucleoside monophosphate metabolic process purine nucleotide metabolic process ribonucleotide metabolic process ribonucleoside monophosphate metabolic process purine nucleoside monophosphate metabolic process phosphate-containing compound metabolic process ribonucleoside monophosphate catabolic process purine ribonucleotide catabolic process phosphorus metabolic process nucleoside monophosphate metabolic process nucleotide catabolic process nucleoside phosphate metabolic process organonitrogen compound catabolic process purine nucleotide catabolic process carbohydrate derivative catabolic process nucleoside monophosphate catabolic process purine-containing compound catabolic process nucleotide metabolic process organic cyclic compound catabolic process IMP catabolic process nucleobase-containing compound catabolic process organophosphate metabolic process purine ribonucleotide metabolic process organic substance catabolic process pyridine nucleoside biosynthetic process pyridine-containing compound metabolic process nicotinamide riboside biosynthetic process nicotinamide riboside metabolic process pyridine-containing compound biosynthetic process pyridine nucleoside metabolic process nicotinic acid riboside metabolic process nicotinic acid riboside biosynthetic process	intracellular anatomical structure cytoplasm cellular anatomical entity

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, G	IPR036412	HAD-like superfamily	Homologous Superfamily
A, G	IPR023214	HAD superfamily	Homologous Superfamily
A, G	IPR009453	IMP-specific 5-nucleotidase	Family
B, D	IPR036412	HAD-like superfamily	Homologous Superfamily
B, D	IPR023214	HAD superfamily	Homologous Superfamily
B, D	IPR009453	IMP-specific 5-nucleotidase	Family
C	IPR036412	HAD-like superfamily	Homologous Superfamily
C	IPR023214	HAD superfamily	Homologous Superfamily
C	IPR009453	IMP-specific 5-nucleotidase	Family
E, H	IPR036412	HAD-like superfamily	Homologous Superfamily
E, H	IPR023214	HAD superfamily	Homologous Superfamily
E, H	IPR009453	IMP-specific 5-nucleotidase	Family
F	IPR036412	HAD-like superfamily	Homologous Superfamily
F	IPR023214	HAD superfamily	Homologous Superfamily
F	IPR009453	IMP-specific 5-nucleotidase	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.