6IYA

Structure of the DNA binding domain of antitoxin CopASO

External Resource: Annotation

Domain Annotation: ECOD Classification
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF01402	e6iyaA1	A: alpha arrays	X: HTH	H: HTH	T: Ribbon-helix-helix	F: PF01402	ECOD (1.6)
B	PF01402	e6iyaB1	A: alpha arrays	X: HTH	H: HTH	T: Ribbon-helix-helix	F: PF01402	ECOD (1.6)
C	PF01402	e6iyaC1	A: alpha arrays	X: HTH	H: HTH	T: Ribbon-helix-helix	F: PF01402	ECOD (1.6)
D	PF01402	e6iyaD1	A: alpha arrays	X: HTH	H: HTH	T: Ribbon-helix-helix	F: PF01402	ECOD (1.6)
E	PF01402	e6iyaE1	A: alpha arrays	X: HTH	H: HTH	T: Ribbon-helix-helix	F: PF01402	ECOD (1.6)
F	PF01402	e6iyaF1	A: alpha arrays	X: HTH	H: HTH	T: Ribbon-helix-helix	F: PF01402	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D, E A, B, C, D, E, F	PF01402	Ribbon-helix-helix protein, copG family (RHH_1)	Ribbon-helix-helix protein, copG family	The structure of this protein repressor, which is the shortest reported to date and the first isolated from a plasmid, has a homodimeric ribbon-helix-helix arrangement [2]. The helix-turn-helix-like structure is involved in dimerisation and not DNA b ...	The structure of this protein repressor, which is the shortest reported to date and the first isolated from a plasmid, has a homodimeric ribbon-helix-helix arrangement [2]. The helix-turn-helix-like structure is involved in dimerisation and not DNA binding as might have been expected [2].	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E A, B, C, D, E, F	Transcriptional regulator CopG family	-	regulation of cellular process cellular biosynthetic process RNA metabolic process regulation of primary metabolic process nucleobase-containing compound metabolic process RNA biosynthetic process nucleic acid biosynthetic process DNA-templated transcription regulation of RNA metabolic process organic substance metabolic process organic substance biosynthetic process regulation of nucleobase-containing compound metabolic process regulation of RNA biosynthetic process regulation of biosynthetic process regulation of cellular process cellular biosynthetic process RNA metabolic process regulation of primary metabolic process nucleobase-containing compound metabolic process RNA biosynthetic process nucleic acid biosynthetic process DNA-templated transcription regulation of RNA metabolic process organic substance metabolic process organic substance biosynthetic process regulation of nucleobase-containing compound metabolic process regulation of RNA biosynthetic process regulation of biosynthetic process regulation of biological process cellular metabolic process biological regulation primary metabolic process regulation of cellular metabolic process regulation of macromolecule metabolic process nucleobase-containing compound biosynthetic process gene expression macromolecule biosynthetic process nucleic acid metabolic process regulation of cellular biosynthetic process organic cyclic compound metabolic process regulation of gene expression biosynthetic process organic cyclic compound biosynthetic process metabolic process regulation of macromolecule biosynthetic process cellular process regulation of DNA-templated transcription macromolecule metabolic process regulation of metabolic process	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E A, B, C, D, E, F	IPR013321	Arc-type ribbon-helix-helix	Homologous Superfamily
A, B, C, D, E A, B, C, D, E, F	IPR010985	Ribbon-helix-helix	Homologous Superfamily
A, B, C, D, E A, B, C, D, E, F	IPR002145	Ribbon-helix-helix protein, CopG	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.