Annotations: 6AKJ

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	ERH-like	8097838	3000225	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	ERH-like	8097838	3000225	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF01133	e6akjA1	A: a+b two layers	X: ERH-like (From Topology)	H: ERH-like (From Topology)	T: ERH-like	F: PF01133	ECOD (1.6)
B	PF01133	e6akjB1	A: a+b two layers	X: ERH-like (From Topology)	H: ERH-like (From Topology)	T: ERH-like	F: PF01133	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF01133	Enhancer of rudimentary (ER)	Enhancer of rudimentary	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	Enhancer of rudimentary homolog,YTH domain-containing protein mmi1 fusion protein	pre-mRNA binding RNA binding binding organic cyclic compound binding nucleic acid binding lncRNA binding protein-RNA adaptor activity protein-macromolecule adaptor activity N6-methyladenosine-containing RNA reader activity molecular adaptor activity protein-containing complex binding CCR4-NOT complex binding DNA binding mRNA binding pre-mRNA binding RNA binding binding organic cyclic compound binding nucleic acid binding lncRNA binding protein-RNA adaptor activity protein-macromolecule adaptor activity N6-methyladenosine-containing RNA reader activity molecular adaptor activity protein-containing complex binding CCR4-NOT complex binding DNA binding mRNA binding pre-mRNA intronic binding molecular function inhibitor activity molecular function regulator activity	regulation of cellular process cellular biosynthetic process negative regulation of biological process negative regulation of cellular metabolic process protein-DNA complex organization cellular component organization organic substance metabolic process chromatin organization organic substance biosynthetic process negative regulation of cellular process chromatin remodeling cellular component organization or biogenesis negative regulation of macromolecule metabolic process regulation of biosynthetic process regulation of cellular process cellular biosynthetic process negative regulation of biological process negative regulation of cellular metabolic process protein-DNA complex organization cellular component organization organic substance metabolic process chromatin organization organic substance biosynthetic process negative regulation of cellular process chromatin remodeling cellular component organization or biogenesis negative regulation of macromolecule metabolic process regulation of biosynthetic process regulation of biological process heterochromatin formation protein-containing complex organization epigenetic regulation of gene expression cellular metabolic process negative regulation of metabolic process biological regulation siRNA-independent facultative heterochromatin formation regulation of cellular metabolic process regulation of macromolecule metabolic process gene expression macromolecule biosynthetic process negative regulation of cellular biosynthetic process regulation of cellular biosynthetic process regulation of gene expression negative regulation of gene expression biosynthetic process negative regulation of biosynthetic process negative regulation of macromolecule biosynthetic process facultative heterochromatin formation negative regulation of gene expression, epigenetic regulation of macromolecule biosynthetic process metabolic process cellular process macromolecule metabolic process regulation of metabolic process catabolic process RNA metabolic process primary metabolic process lncRNA catabolic process nucleic acid metabolic process macromolecule catabolic process organic cyclic compound catabolic process nucleobase-containing compound catabolic process nucleobase-containing compound metabolic process organic cyclic compound metabolic process nucleic acid catabolic process organic substance catabolic process RNA catabolic process mRNA catabolic process nuclear RNA surveillance nuclear mRNA surveillance of mRNA 3'-end processing RNA surveillance nuclear-transcribed mRNA catabolic process nuclear mRNA surveillance mRNA metabolic process protein-containing complex disassembly regulation of protein-containing complex disassembly regulation of primary metabolic process DNA-templated transcription regulation of termination of RNA polymerase II transcription, poly(A)-coupled regulation of RNA metabolic process transcription by RNA polymerase II regulation of nucleobase-containing compound metabolic process cellular component disassembly termination of RNA polymerase II transcription, poly(A)-coupled organic cyclic compound biosynthetic process regulation of termination of DNA-templated transcription termination of RNA polymerase II transcription regulation of termination of RNA polymerase II transcription regulation of cellular component organization DNA-templated transcription termination RNA biosynthetic process nucleic acid biosynthetic process regulation of RNA biosynthetic process nucleobase-containing compound biosynthetic process nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts RNA 3'-end processing RNA processing regulatory ncRNA 3'-end processing regulatory ncRNA processing regulatory ncRNA-mediated gene silencing positive regulation of metabolic process post-transcriptional regulation of gene expression positive regulation of macromolecule metabolic process regulation of biological quality positive regulation of nucleobase-containing compound metabolic process positive regulation of mRNA metabolic process positive regulation of RNA metabolic process positive regulation of biological process mRNA destabilization regulation of mRNA catabolic process RNA destabilization regulation of catabolic process positive regulation of catabolic process regulation of mRNA stability positive regulation of mRNA catabolic process regulation of RNA stability regulation of mRNA metabolic process nuclear mRNA surveillance of spliceosomal pre-mRNA splicing regulation of heterochromatin formation regulation of chromatin organization regulation of siRNA-independent facultative heterochromatin formation	protein-containing complex intracellular anatomical structure protein-DNA complex heterochromatin island chromatin chromosome cellular anatomical entity heterochromatin intracellular organelle organelle intracellular non-membrane-bounded organelle non-membrane-bounded organelle membrane-bounded organelle nucleus protein-containing complex intracellular anatomical structure protein-DNA complex heterochromatin island chromatin chromosome cellular anatomical entity heterochromatin intracellular organelle organelle intracellular non-membrane-bounded organelle non-membrane-bounded organelle membrane-bounded organelle nucleus membrane-enclosed lumen intracellular membrane-bounded organelle nuclear exosome focus intracellular organelle lumen nuclear body nucleoplasm organelle lumen nuclear lumen cytoplasm nuclear protein-containing complex Mei2 nuclear dot complex ribonucleoprotein complex ascospore-type prospore ascospore-type prospore nucleus intracellular immature spore rDNA heterochromatin

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR007275	YTH domain	Domain
A, B	IPR035912	Enhancer of rudimentary superfamily	Homologous Superfamily
A, B	IPR000781	Enhancer of rudimentary	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.