5Z2H

Structure of Dictyostelium discoideum mitochondrial calcium uniporter N-terminal domain(DdMCU-NTD)

External Resource: Annotation

Domain Annotation: ECOD Classification
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	F_UNCLASSIFIED	e5z2hA1	A: alpha arrays	X: HTH	H: HTH	T: winged	F: F_UNCLASSIFIED	ECOD (1.6)
B	F_UNCLASSIFIED	e5z2hB1	A: alpha arrays	X: HTH	H: HTH	T: winged	F: F_UNCLASSIFIED	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF04678	Mitochondrial calcium uniporter (MCU)	Mitochondrial calcium uniporter	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	Dictyostelium discoideum mitochondrial calcium uniporter	active transmembrane transporter activity transporter activity uniporter activity transmembrane transporter activity secondary active transmembrane transporter activity cation binding ion binding binding calcium ion binding metal ion binding small molecule binding calcium channel activity monoatomic cation transmembrane transporter activity monoatomic ion channel activity active transmembrane transporter activity transporter activity uniporter activity transmembrane transporter activity secondary active transmembrane transporter activity cation binding ion binding binding calcium ion binding metal ion binding small molecule binding calcium channel activity monoatomic cation transmembrane transporter activity monoatomic ion channel activity monoatomic cation channel activity passive transmembrane transporter activity calcium ion transmembrane transporter activity inorganic molecular entity transmembrane transporter activity channel activity inorganic cation transmembrane transporter activity monoatomic ion transmembrane transporter activity metal ion transmembrane transporter activity	transport monoatomic ion transmembrane transport inorganic ion transmembrane transport mitochondrial transmembrane transport establishment of localization calcium ion transport metal ion transport inorganic cation transmembrane transport transmembrane transport monoatomic cation transmembrane transport localization import into the mitochondrion mitochondrial calcium ion transmembrane transport monoatomic ion transport transport monoatomic ion transmembrane transport inorganic ion transmembrane transport mitochondrial transmembrane transport establishment of localization calcium ion transport metal ion transport inorganic cation transmembrane transport transmembrane transport monoatomic cation transmembrane transport localization import into the mitochondrion mitochondrial calcium ion transmembrane transport monoatomic ion transport cellular process calcium import into the mitochondrion monoatomic cation transport calcium ion transmembrane transport mitochondrial transport mitochondrial calcium ion homeostasis inorganic ion homeostasis intracellular calcium ion homeostasis homeostatic process calcium ion homeostasis cellular homeostasis chemical homeostasis intracellular monoatomic cation homeostasis monoatomic ion homeostasis intracellular chemical homeostasis monoatomic cation homeostasis intracellular monoatomic ion homeostasis	membrane-bounded organelle intracellular organelle intracellular anatomical structure mitochondrion organelle cytoplasm cellular anatomical entity intracellular membrane-bounded organelle protein-containing complex mitochondrial membrane organelle inner membrane membrane protein complex transporter complex organelle envelope membrane-bounded organelle intracellular organelle intracellular anatomical structure mitochondrion organelle cytoplasm cellular anatomical entity intracellular membrane-bounded organelle protein-containing complex mitochondrial membrane organelle inner membrane membrane protein complex transporter complex organelle envelope uniplex complex mitochondrial protein-containing complex membrane cation channel complex mitochondrial inner membrane inner mitochondrial membrane protein complex transmembrane transporter complex mitochondrial envelope organelle membrane calcium channel complex monoatomic ion channel complex

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR039055	MCU family	Family
A, B	IPR006769	Calcium uniporter protein, C-terminal	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.