Annotations: 5XT5

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A [auth D]	d5xt5d_	Alpha and beta proteins (a+b)	SufE/NifU	SufE/NifU	NifU/IscU domain	automated matches	(Bacillus subtilis subsp. subtilis str. 168 ) [TaxId: 224308 ],	SCOPe (2.08)
D [auth C]	d5xt5c_	Alpha and beta proteins (a+b)	SufE/NifU	SufE/NifU	NifU/IscU domain	automated matches	(Bacillus subtilis subsp. subtilis str. 168 ) [TaxId: 224308 ],	SCOPe (2.08)
B [auth A]	d5xt5a1	Alpha and beta proteins (a/b)	PLP-dependent transferase-like	PLP-dependent transferases	automated matches	automated matches	(Bacillus subtilis subsp. subtilis str. 168 ) [TaxId: 224308 ],	SCOPe (2.08)
B [auth A]	d5xt5a2	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Bacillus subtilis subsp. subtilis str. 168 ) [TaxId: 224308 ],	SCOPe (2.08)
C [auth B]	d5xt5b_	Alpha and beta proteins (a/b)	PLP-dependent transferase-like	PLP-dependent transferases	automated matches	automated matches	(Bacillus subtilis subsp. subtilis str. 168 ) [TaxId: 224308 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A [auth D]	SCOP2B Superfamily	SufE/NifU	8043955	3000436	SCOP2B (2022-06-29)
D [auth C]	SCOP2B Superfamily	SufE/NifU	8043955	3000436	SCOP2B (2022-06-29)
B [auth A]	SCOP2 Family	Cystathionine synthase-like	8074689	4000672	SCOP2 (2022-06-29)
B [auth A]	SCOP2 Superfamily	PLP-dependent transferases	8074690	3000954	SCOP2 (2022-06-29)
C [auth B]	SCOP2B Superfamily	PLP-dependent transferases	8074690	3000954	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A [auth D]	PF01592	e5xt5D1	A: a+b two layers	X: FAD-linked reductases, C-terminal domain-like	H: SufE/NifU (From Topology)	T: SufE/NifU	F: PF01592	ECOD (1.6)
D [auth C]	PF01592	e5xt5C1	A: a+b two layers	X: FAD-linked reductases, C-terminal domain-like	H: SufE/NifU (From Topology)	T: SufE/NifU	F: PF01592	ECOD (1.6)
B [auth A]	PF00266	e5xt5A1	A: a+b two layers	X: C-terminal domain in some PLP-dependent transferases (From Topology)	H: C-terminal domain in some PLP-dependent transferases (From Topology)	T: C-terminal domain in some PLP-dependent transferases	F: PF00266	ECOD (1.6)
B [auth A]	PF00266	e5xt5A2	A: a/b three-layered sandwiches	X: PLP-dependent transferases (From Topology)	H: PLP-dependent transferases (From Topology)	T: PLP-dependent transferases	F: PF00266	ECOD (1.6)
C [auth B]	PF00266	e5xt5B1	A: a+b two layers	X: C-terminal domain in some PLP-dependent transferases (From Topology)	H: C-terminal domain in some PLP-dependent transferases (From Topology)	T: C-terminal domain in some PLP-dependent transferases	F: PF00266	ECOD (1.6)
C [auth B]	PF00266	e5xt5B2	A: a/b three-layered sandwiches	X: PLP-dependent transferases (From Topology)	H: PLP-dependent transferases (From Topology)	T: PLP-dependent transferases	F: PF00266	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A [auth D]	3.90.1010.10	Alpha Beta	Alpha-Beta Complex	Sufe protein. Chain: A		CATH (4.3.0)
D [auth C]	3.90.1010.10	Alpha Beta	Alpha-Beta Complex	Sufe protein. Chain: A		CATH (4.3.0)
B [auth A]	3.40.640.10	Alpha Beta	3-Layer(aba) Sandwich	Aspartate Aminotransferase	domain 2	CATH (utative)
C [auth B]	3.40.640.10	Alpha Beta	3-Layer(aba) Sandwich	Aspartate Aminotransferase	domain 2	CATH (utative)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A [auth D], D [auth C]	PF01592	NifU-like N terminal domain (NifU_N)	NifU-like N terminal domain	-	Family
B [auth A], C [auth B]	PF00266	Aminotransferase class-V (Aminotran_5)	Aminotransferase class-V	This domain is found in amino transferases, and other enzymes including cysteine desulphurase EC:4.4.1.-.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A [auth D], D [auth C]	Zinc-dependent sulfurtransferase SufU	cation binding transition metal ion binding iron ion binding ion binding binding ferrous iron binding metal ion binding small molecule binding iron-sulfur cluster binding 2 iron, 2 sulfur cluster binding metal cluster binding transferase activity catalytic activity	intracellular iron ion homeostasis inorganic ion homeostasis cellular homeostasis chemical homeostasis homeostatic process intracellular monoatomic cation homeostasis monoatomic ion homeostasis intracellular chemical homeostasis monoatomic cation homeostasis intracellular monoatomic ion homeostasis cellular component biogenesis cellular component organization metallo-sulfur cluster assembly cellular component assembly intracellular iron ion homeostasis inorganic ion homeostasis cellular homeostasis chemical homeostasis homeostatic process intracellular monoatomic cation homeostasis monoatomic ion homeostasis intracellular chemical homeostasis monoatomic cation homeostasis intracellular monoatomic ion homeostasis cellular component biogenesis cellular component organization metallo-sulfur cluster assembly cellular component assembly iron-sulfur cluster assembly cellular process cellular component organization or biogenesis	intracellular anatomical structure cytoplasm cellular anatomical entity
B [auth A], C [auth B]	Cysteine desulfurase SufS	cysteine desulfurase activity sulfurtransferase activity transferase activity, transferring sulphur-containing groups transferase activity catalytic activity vitamin binding vitamin B6 binding pyridoxal phosphate binding ion binding binding organic cyclic compound binding anion binding heterocyclic compound binding small molecule binding	organonitrogen compound metabolic process oxoacid metabolic process sulfur amino acid metabolic process cellular metabolic process carboxylic acid metabolic process amino acid metabolic process primary metabolic process organic acid metabolic process alpha-amino acid metabolic process cysteine metabolic process organic substance metabolic process metabolic process small molecule metabolic process cellular process organonitrogen compound metabolic process oxoacid metabolic process sulfur amino acid metabolic process cellular metabolic process carboxylic acid metabolic process amino acid metabolic process primary metabolic process organic acid metabolic process alpha-amino acid metabolic process cysteine metabolic process organic substance metabolic process metabolic process small molecule metabolic process cellular process sulfur compound metabolic process	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A [auth D], D [auth C]	IPR002871	NIF system FeS cluster assembly, NifU, N-terminal	Domain
B [auth A], C [auth B]	IPR020578	Aminotransferase class-V, pyridoxal-phosphate binding site	Binding Site
B [auth A], C [auth B]	IPR015424	Pyridoxal phosphate-dependent transferase	Homologous Superfamily
B [auth A], C [auth B]	IPR016454	Cysteine desulfurase	Family
B [auth A], C [auth B]	IPR015421	Pyridoxal phosphate-dependent transferase, major domain	Homologous Superfamily
B [auth A], C [auth B]	IPR010970	Cysteine desulfurase, SufS	Family
B [auth A], C [auth B]	IPR015422	Pyridoxal phosphate-dependent transferase, small domain	Homologous Superfamily
B [auth A], C [auth B]	IPR000192	Aminotransferase class V domain	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.