5VWY
Bak core latch dimer in complex with Bim-h3Pc-RT
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Chains | Type | Family Name | Domain Identifier | Family Identifier | Provenance Source (Version) |
---|---|---|---|---|---|
B | SCOP2B Superfamily | BH3 domain | 8055788 | 3002075 | SCOP2B (2022-06-29) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | PF00452 | e5vwyA1 | A: alpha arrays | X: Toxins' membrane translocation domains | H: Bcl-2 inhibitors of programmed cell death (From Topology) | T: Bcl-2 inhibitors of programmed cell death | F: PF00452 | ECOD (1.6) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF00452 | Apoptosis regulator proteins, Bcl-2 family (Bcl-2) | Apoptosis regulator proteins, Bcl-2 family | - | Family | |
PF08945 | Bcl-x interacting, BH3 domain (Bclx_interact) | Bcl-x interacting, BH3 domain | This domain is a long alpha helix, required for interaction with Bcl-x. It is found in BAM, Bim and Bcl2-like protein 11 [1]. This domain is also known as the BH3 domain between residues 146 and 161. | Domain |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR036834 | Bcl-2-like superfamily | Homologous Superfamily | |
IPR002475 | Bcl2-like | Family | |
IPR020728 | Apoptosis regulator, Bcl-2, BH3 motif, conserved site | Conserved Site | |
IPR020726 | Apoptosis regulator, Bcl-2, BH2 motif, conserved site | Conserved Site | |
IPR046371 | Bcl-2, Bcl-2 homology region 1-3 | Domain | |
IPR026298 | Bcl-2 family | Family | |
IPR020717 | Apoptosis regulator, Bcl-2, BH1 motif, conserved site | Conserved Site | |
IPR014771 | Apoptosis, Bim N-terminal | Domain | |
IPR017288 | Bcl-2-like protein 11 | Family | |
IPR015040 | Bcl-x interacting, BH3 domain | Domain |